Clinical and Practical Psychopharmacology
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Clinical and Practical Psychopharmacology
Antidepressant Exposure During Pregnancy and Risk of Autism, 2
October 25, 2017
This installment of the Clinical and Practical Psychopharmacology column continues looking at the evidence regarding autism and use of antidepressants during pregnancy. Dr Andrade discusses whether 5 new studies…
Clinical and Practical Psychopharmacology
Antidepressant Exposure During Pregnancy and Risk of Autism, 1
September 26, 2017
In this installment of his Clinical and Practical Psychopharmacology column, Dr Andrade provides a meta-review of 6 meta-analyses examining the risk of autism spectrum disorder associated with use of…
Clinical and Practical Psychopharmacology
Ketamine for Depression, 5: Pharmacokinetic and Pharmacodynamic Drug Interactions
August 23, 2017
This installment of Dr Andrade’s series on the use of ketamine for depression considers possible interactions of ketamine with other medications—both what we know and what we don’ t…
Clinical and Practical Psychopharmacology
Ketamine for Depression, 3: Does Chirality Matter?
June 28, 2017
Ketamine is a racemic mixture of R- and S-enantiomers, and S-ketamine has greater analgesic and anesthetic action than R-ketamine. In this month’s Clinical and Practical Psychopharmacology column, Dr Andrade…
Clinical and Practical Psychopharmacology
Ketamine for Depression, 2: Diagnostic and Contextual Indications
May 24, 2017
In this article, Dr Andrade looks at the diagnostic indications for use of ketamine as an antidepressant, as well as specific clinical situations in which ketamine may be particularly…
Clinical and Practical Psychopharmacology
Ketamine for Depression, 1: Efficacy, Adverse Effects, and Mechanism of Action
April 26, 2017
In this issue of Clinical and Practical Psychopharmacology, Dr Andrade outlines clinical aspects of ketamine, an anesthetic drug that, at subanesthetic doses, has demonstrated rapid response in even treatment-resistant…
Clinical and Practical Psychopharmacology
Offspring Outcomes in Antidepressant-Treated Pregnancies
March 29, 2017
Both untreated depression and prenatal exposure to antidepressants have been associated with adverse outcomes. In this month’s column, Dr Andrade describes possible study design’ ’related contributors that are important…
Clinical and Practical Psychopharmacology
Propensity Score Matching in Nonrandomized Studies
February 22, 2017
Propensity score matching, or the probability that a subject will receive a particular treatment, is one way to address baseline differences between treatment groups in observational studies. In this…
Clinical and Practical Psychopharmacology
Comparing Efficacy of Antipsychotic Drugs in Schizophrenia
December 28, 2016
How do antipsychotics compare to one another in terms of efficacy? Which ones are particularly effective for treatment-resistant patients? In this month’s column, Dr Andrade considers the findings of…
