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Cholesterol, Obesity, and Metabolic Syndrome in Epileptic Patients
Original Research

June 7, 2022

This study compared cardiovascular risk factors in patients with epilepsy with those of non-epileptic neurologic patients to determine their association with antiepileptic drug therapy.
Inam E. Khuda, Saima Nazish, Mohammad Ayub Zeeshan, et al
JCP
Transdermal HP-3070 for Hostility in Schizophrenia
Original Research

June 6, 2022

Schizophrenia is sometimes accompanied by aggressive, hostile behavior, particularly during the acute phase. This post hoc analysis of a phase 3 study examines the efficacy of transdermal asenapine (HP-3070)...
Leslie Citrome, Marina Komaroff, Brittney Starling, et al
JCP
Suicide Risk in a National VA Sample
Original Research

June 6, 2022

Predicting suicide is difficult, as suicidal behavior is not linked solely to any single behavior or psychiatric diagnosis. This study compared risk of suicidal behavior among a transdiagnostic sample...
Alan C. Swann, David P. Graham, Anna V. Wilkinson, et al
JCP
Long-term Outcomes of Early Use of LAIs in Schizophrenia
Original Research

June 1, 2022

Using data from the Taiwan National Health Insurance Research Database, the authors compared long-term effectiveness of switching to long-acting injectable antipsychotics versus remaining on oral antipsychotics.
Su-Chen Fang, Cheng-Yi Huang, Yu-Hsuan Joni Shao
PCC
Sleep in Older Adults During the COVID-19 Pandemic
Original Research

May 31, 2022

This study measured the impact of the COVID-19 pandemic on sleep and how it correlates with the feeling of isolation in individuals aged 50 years and older.
Catarina Rodrigues Cordeiro, Pedro Câmara Pestana, Beatriz Côrte-Real, et al
JCP
Efficacy and Safety of AXS-05 (Dextromethorphan-Bupropion) in MDD
Original Research

May 30, 2022

Altered glutamatergic neurotransmission has been implicated in the pathogenesis of depression. This phase 3 trial evaluated the efficacy and safety of AXS-05 (dextromethorphan-bupropion) in the treatment of major depressive...
Dan V. Iosifescu, Amanda Jones, Cedric O’Gorman, et al
PCC
Attachment Styles and Mental Health in Adolescents
Original Research

May 19, 2022

This study assessed the association between insecure attachment styles and depression, social anxiety, and suicidal ideation among Lebanese adolescents.
Nour Fattouh, Chadia Haddad, Pascale Salameh, et al
JCP
Clozapine Use in Singapore and Hong Kong
Original Research

May 18, 2022

This survey investigated clinicians’ use of clozapine for schizophrenia, beliefs about its effectiveness, and concerns regarding this medication.
Shushan Zheng, Jimmy Lee, Sherry Kit Wa Chan
JCP
Youth Aware of Mental Health (YAM) Intervention
Original Research

May 16, 2022

Youth Aware of Mental Health (YAM) is a manualized universal intervention designed to increase mental health awareness about protective factors, depression and suicide, and coping skills. This study assessed...
Madhukar H. Trivedi, Karabi Nandy, Taryn L. Mayes, et al
JCP
Eating Disorders in Youth With Bipolar Disorder
Original Research

May 11, 2022

Research has shown the importance of comorbid eating disorders (ED) in bipolar disorder (BD), though most studies have focused on adults. This study examined the prevalence and correlates of...
Diana Khoubaeva, Mikaela K. Dimick, Jessica L. Roane, et al
JCP
Antipsychotic Efficacy of KarXT (Xanomeline−Trospium)
Original Research

image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ May 11, 2022

This post hoc analysis of phase 2 data evaluated rates and time course of response with the new combination oral agent KarXT (xanomeline−trospium) in the treatment of schizophrenia.
Peter J. Weiden, Alan Breier, Sarah Kavanagh, et al
PCC
Social and Emotional Health of College Students and COVID-19
Original Research

May 10, 2022

This study assessed the social and emotional health of university students in India as influenced by COVID-19 test results and the experience of isolation or quarantine.
Anandi Sarkar, Elizabeth Jasmine, Sherin Lee Thomas, et al
JCP
Daily Dose Effects of Risperidone on Metabolic Parameters
Original Research

May 9, 2022

This study investigated whether dose is a factor in the development of metabolic side effects with atypical antipsychotics.
Marianna Piras, Céline Dubath, Mehdi Gholam, et al
PCC
Resilience, Coping, Distress, and COVID-19
Original Research

May 5, 2022

The authors of this study assessed psychological resilience, coping, and related psychological distress in COVID-19 patients admitted to the hospital.
Mitthat Miglani, Palak Upadhyay, Rajesh Mahajan, et al
PCC
Psychological Morbidity Among COVID-19 Survivors
Original Research

May 3, 2022

This study explored the psychological status of health care workers after recovery from COVID-19 and examined the sociodemographic and clinical factors associated with psychiatric morbidity.
N. A. Uvais, Shamsudeen Moideen, Sooraj Rajagopal, et al
JCP
Epilepsy and Suicide Attempt
Original Research

May 2, 2022

From a sample of 1,229 adults who attempted suicide, this study found an elevated frequency of epilepsy and identified clinical factors that might play a role.
Basma Akrout Brizard, Philippe Courtet, Isabelle Jaussent, et al
JCP
Receipt of Antidepressants and Retention in Buprenorphine Treatment for OUD
Original Research

April 27, 2022

This study investigated whether receiving antidepressants increases the chance that patients with opioid use disorder will remain on buprenorphine treatment.
Kun Zhang, Christopher M. Jones, Wilson M. Compton, et al
JCP
Economic Burden of PTSD in the US
Original Research

April 25, 2022

Studies on the economic burden of posttraumatic stress disorder (PTSD) mostly focus on military populations and/or direct health care costs. This study estimated the economic burden of PTSD in...
Lori L. Davis, Jeff Schein, Martin Cloutier, et al
PCC
Psychocutaneous Medicine in Iraq
Original Research

April 21, 2022

In this study, the authors evaluated the knowledge and attitudes of Iraqi dermatologists regarding understanding, diagnosing, and treating psychocutaneous disorders.
Lama Altaha, Mohammad Jafferany, Angubeen Khan
JCP
Transdiagnostic PRS Prediction of Mood Disorders
Original Research

April 20, 2022

Mood disorders often co-occur with behavior disorders in children and adolescents. This study explored if polygenic risk scores based on external genome-wide association studies of these disorders could improve...
Eric J. Barnett, Joseph Biederman, Alysa E. Doyle, et al
PCC
Care Management Intervention for Noncardiac Chest Pain
Original Research

April 19, 2022

This study describes the development, implementation, and preliminary feasibility of an 8-week multicomponent care management intervention for noncardiac chest pain.
Elizabeth N. Madva, Christopher M. Celano, Sonia Kim, et al
JCP
Co-Occurring Depression and Response During OUD Treatment
Original Research

April 18, 2022

This study looked at the relationship between opioid use disorder treatment and depression, and whether remission of depression is associated with lower relapse risk.
Peter J. Na, Jennifer Scodes, Marc Fishman, et al
JCP
ECT and Death by Suicide
Original Research

April 13, 2022

It is unclear if a course of electroconvulsive therapy (ECT) is associated with a decreased risk of death by suicide. This study examined the association of adequate exposure to...
Bradley V. Watts, Talya Peltzman, Brian Shiner
JCP
Effects of a Digital Medicine System on Psychiatric Hospitalization Rates for Adults With Schizophrenia
Original Research

April 11, 2022

This clinical trial investigated whether hospitalization rates improved when patients with schizophrenia were treated via a digital medicine system (aripiprazole tablets with sensor) versus oral standard-of-care therapy.
Elan A. Cohen, Taisa Skubiak, Dusica Hadzi Boskovic, et al

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