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JCP
Brexpiprazole in Patients With MDD and Prediabetes
Original Research

August 28, 2023

Some atypical antipsychotics, while efficacious as adjunctive treatments in major depressive disorder (MDD), can lead to adverse effects and weight gain. Adjunctive brexpiprazole had a limited impact on metabolic...
John W. Newcomer, Stine R. Meehan, Dalei Chen, et al
JCP
Alcohol Use Disorder Treatment in Sexually and Gender Diverse Patients
Original Research

August 28, 2023

Sexually and gender diverse (SGD) patients had significantly higher rates of both AUD diagnosis and care utilization compared with non-SGD patients.
Michal J. McDowell, Dana S. King, Sy Gitin, et al
JCP
Clozapine Delay and Schizophrenia Outcomes
Original Research

August 23, 2023

Clozapine is the drug of choice for treatment-resistant schizophrenia, but delays in initiation and underutilization may hinder its effectiveness. This study examined whether delay in clozapine initiation led to...
Claire Law, Yuen Mei See, Jie Yin Yee, et al
JCP
Delirium and Mortality in COVID-19 Patients
Original Research

August 21, 2023

COVID-19 patients with early onset delirium had a 2-fold increased mortality risk—both in-hospital and after discharge—than those without delirium.
Caterina Trevisan, Giulia Grande, Paola Rebora, et al
JCP
Adjunctive Cariprazine for MDD With Inadequate Response to Antidepressants
Original Research

August 16, 2023

This study assessed the efficacy of adjunctive use of cariprazine, an atypical antipsychotic, in MDD patients with inadequate response to antidepressants.
Robert Riesenberg, Paul P. Yeung, Ludmyla Rekeda, et al
JCP
Fiscal Impact of Schizophrenia From a Government Perspective
Original Research

August 9, 2023

This analysis revealed that the lifetime fiscal loss to the government was $1,540,042 for each person with schizophrenia.
Rui Martins, Aditi Kadakia, G. Rhys Williams, et al
JCP
Antihypertensive Medications and PTSD
Original Research

August 2, 2023

Calcium channel blockers were linked to decreased incidence of PTSD; the association was not found for any other antihypertensive medication classes.
Jaimie L. Gradus, Meghan L. Smith, Péter Szentkúti, et al
PCC
The NIMH Research Portfolio: An Update
Original Research

August 1, 2023

NIMH has continued to prioritize basic research over clinical trials, resulting in a decline in funding for possible treatments for psychiatric diseases.
Fuller Torrey, Wendy W. Simmons, Lisa Dailey
JCP
Hepatitis C Screening and Treatment in Psychiatry Inpatients
Original Research

July 31, 2023

Of people admitted to a psychiatric unit, 4.9% had a positive HCV antibody screening result, underlining the need to screen psychiatric inpatients for hepatitis C.
Erin Mandel, Mia J. Biondi, Andrew Mendlowitz, et al
JCP
Race, Ethnicity, and ED Disposition for Mental Health Visits
Original Research

July 26, 2023

Black patients, especially Black male patients, are overrepresented in inpatient psychiatry. This study examined biases in admission rates among Black patients and, specifically, Black male patients with or without...
Nina Gao, Mark Olfson
JCP
Rumination, Resilience, and Depression in Adolescents
Original Research

July 26, 2023

This study explored the mediating role of psychological resilience in the effects of rumination on depression in adolescents with mood disorders and found rumination and resilience to be risk...
Dianying Liu, Yang Wang, Peng Xie, et al
JCP
Public Health Nurse-Delivered Group CBT for PPD
Original Research

July 24, 2023

The increase in postpartum depression during the pandemic highlights a need for accessible interventions. In this study, online group CBT significantly reduced depression, worry, and rejection and pathological anger...
Kathryn Huh, Haley Layton, Calan D. Savoy, et al
PCC
External Ear and Minor Physical Anomalies in Patients With Depression
Original Research

July 20, 2023

External ear anomalies are more prevalent in patients with depressive disorder, supporting the neurodevelopmental theory of depression.
Puneet Kumar Soni, Lokesh Kumar Singh, Ripu Daman Arora, et al
PCC
Quality of Life of Caregivers of Patients With Mental Illness
Original Research

July 18, 2023

The care of a person with mental illness involves multiple challenges, leading to negative impacts on the caregivers’ mental health.
Semaan Semaan, Chadia Haddad, Emmanuelle Awad, et al
JCP
Inflammatory Features in Prodromal Psychosis
Original Research

July 17, 2023

This study suggests that niacin response tests should be considered in early psychosis identification and prediction.
TianHong Zhang, XuDong Xiao, HaiSu Wu, et al
PCC
Managing ADHD During the COVID-19 Pandemic
Original Research

July 13, 2023

Adults with ADHD reported increased difficulty in managing their symptoms during the COVID-19 pandemic.
Subhara Raveendran, Mary C. Burke, Karen Klahn, et al
JCP
Tonic Immobility and Peritraumatic Dissociation in PTSD
Original Research

July 12, 2023

Tonic immobility and peritraumatic dissociation in reaction to trauma are associated with later psychopathology. This study suggests that interventions targeting these reactions could reduce future PTSD risk.
Sarah Bøgelund Dokkedahl, Yael Lahav
JCP
SNRIs and Hypertensive Disorders of Pregnancy
Original Research

July 10, 2023

Hypertensive disorders of pregnancy (HDP) are a major complication. In this study, the risk of HDP with SNRIs (9.5%) was significantly higher than with SSRIs (5.5%).
Justine Benevent, Mélanie Araujo, Sudip Karki, et al
JCP
Cardiovascular Risk by SMI Subtype
Original Research

July 5, 2023

Cardiovascular disease is the leading cause of death for people with serious mental illness. A clinical decision support tool produced a significant relative reduction in total modifiable cardiovascular risk...
Rebecca C. Rossom, A. Lauren Crain, Stephen Waring, et al
PCC
Functional Disability in US Military Veterans
Original Research

July 4, 2023

Improved identification and integrated clinical management of sociodemographic, military, and health risk factors may help mitigate disability risk and promote the maintenance of functional capacity in US veterans.
Andrew W. Meisler, Mayumi O. Gianoli, Peter J. Na, et al
JCP
Subcallosal Cingulate Gyrus Deep Brain Stimulation for TRD
Original Research

June 28, 2023

DBS targeting the subcallosal cingulate gyrus to treat depressive symptoms resulted in response and remission rates of 75% and 62.5%.
Carlo Alemany, Dolors Puigdemont, Ana Martín-Blanco, et al
PCC
Initiative to Improve Antipsychotic Metabolic Monitoring
Original Research

June 27, 2023

Interprofessional monthly care conferences can improve coordination of care across mental health and primary care settings.
Mark E. Schneiderhan, Carolyn O’Donnell, Sarah K. Jackson, et al
JCP
Vitamin D3 and Omega-3 Fatty Acids for Depression Prevention
Original Research

June 26, 2023

Although several lines of evidence suggest that vitamin D3 and omega-3 fatty acids promote mood health, neither supplement showed benefits for indicated and selective prevention of late-life depression.
Chirag M. Vyas, David Mischoulon, Grace Chang, et al
PCC
Suicidal Behavior in First-Episode Schizophrenia
Original Research

June 20, 2023

Suicidal behavior is most prevalent in the early phases of illness in first-episode schizophrenia, particularly during hospital admission.
Sangha Mitra Godi, S. Nagaraju, Vadaparty Padma

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