Balwinder Singh, MD, MS

With its antisuicidal effect and low cost, lithium can be an effective alternative to other MDD augmentation strategies when antidepressants are not enough.

Are ketamine and esketamine equally efficacious? This observational study compares the efficacy of subanesthetic intravenous ketamine with that of intranasal esketamine for treatment-resistant depression in a real-world clinical setting.

This ASCP Corner article reviews the potential benefits and harms of thyroid hormone therapy in the management of unipolar and bipolar depression.