David McDonnell, MD | Psychiatrist.com

Olanzapine/Samidorphan Mitigates Weight Gain in Early Illness

Original Research

Olanzapine/Samidorphan Mitigates Weight Gain in Early Illness

March 22, 2023

In patients with early-phase schizophrenia or bipolar disorder, combination olanzapine and samidorphan resulted in less weight gain at week 12 than olanzapine alone. Antipsychotic efficacy was similar between the...

René S. Kahn, John M. Kane, Christoph U. Correll, et al

Original Research

Olanzapine Plus Samidorphan in Schizophrenia With AUD

March 10, 2020

Alcohol use disorder is comorbid in 33% of US patients with schizophrenia. Testing the tolerability of olanzapine and samidorphan until the first event of exacerbation of disease symptoms is...

Mary F. Brunette, Christoph U. Correll, Stephanie S. O' Malley, et al

Original Research

Olanzapine/Samidorphan for Schizophrenia

March 3, 2020

Read a study evaluating the antipsychotic efficacy and safety of OLZ/SAM compared with placebo in patients with an acute exacerbation of schizophrenia.

Steven G. Potkin, Jelena Kunovac, Bernard L. Silverman, et al

Original Research

An 8-Week, Double-Blind, Randomized, Placebo-Controlled Study of Olanzapine Long-Acting Injection in Acutely Ill Patients With Schizophrenia

May 11, 2008

John Lauriello, Tim Lambert, Scott Andersen, et al