Devon Johnson, MD
Department of Psychiatry, University of California, San Diego, California
Case Report
Serotonin Syndrome and Dextromethorphan Toxicity Caused by Fluoxetine and Bupropion-Dextromethorphan Interaction
April 3, 2024
Addition of bupropion-dextromethorphan (BUP/DXM) to existing fluoxetine treatment resulted in serotonin syndrome within 3 days, with symptoms prompting presentation to the ED 5 days after discontinuation of BUP/DXM.
