George I. Papakostas, MD
Clinical Trials Network and Institute, Department of Psychiatry, Massachusetts General Hospital; and Department of Psychiatry, Harvard Medical School, Boston, Massachusetts
Original Research
Effect of Benzodiazepines on Antidepressant Effects of Ketamine
November 14, 2022
Findings of studies examining the impact of benzodiazepines on antidepressant effects of ketamine are contradictory. This study assessed whether concomitant oral benzodiazepines differentially affected treatment response to ketamine versus...
Insight videos
Talking With Patients Who Have Major Depressive Disorder About the Benefits and Risks Associated With Atypical Antipsychotics
April 6, 2021
Learn how to talk with patients who have major depressive disorder about antipsychotic treatment in a way that is clear and balanced and addresses patients’ potential concerns about taking...
Original Research
Adjunctive Pimavanserin and Sleep/Wakefulness in MDD
December 1, 2020
Adjunctive pimavanserin can reduce depressive symptoms and improve function in patients with major depression and inadequate antidepressant response. This analysis evaluated the effects of adjunctive pimavanserin on sleep/wakefulness disturbances.
DELETE eReport
Augmentation and Adjunctive Strategies for Inadequate Response in MDD
May 12, 2020
When a patient with major depressive disorder isn't responding to antidepressant treatment, what are your next moves? In this activity, learn from the experts about augmentation and adjunctive strategies.
