Maurizio Fava, MD

Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts

JCP
Original Research

October 13, 2020

This double-blind, randomized, crossover study investigated the effects of a supratherapeutic dose of SPN-812, a drug currently under investigation as a treatment for ADHD, on cardiac repolarization (QTc) in...
Azmi Nasser, Shamia L. Faison, Tesfaye Liranso, et al
JCP
Original Research

June 9, 2020

Postmenopausal women may be deficient in the neuroactive steroid allopregnanolone. This study examined oral ganaxolone, an allopregnanolone analog, as augmentation therapy in postmenopausal women with inadequate response to traditional...
Laura E. Dichtel, Maren Nyer, Christina Dording, et al
JCP
Meta-Analysis

May 26, 2020

The FDA has now approved intranasal esketamine as augmention in treatment-resistant depression, and recent studies of its efficacy have been encouraging. This meta-analysis synthesizes the evidence to provide an...
George I. Papakostas, Naji C. Salloum, Rebecca S. Hock, et al
JCP
Original Research

September 24, 2019

The use of atypical antipsychotics as adjunctive treatment for nonresponsive depression is limited by their side effects. This study explores whether pimavanserin can be both an efficacious and tolerable...
Maurizio Fava, Bryan Dirks, Marlene P. Freeman, et al
JCP
Original Research

July 25, 2017

Cognitive deficits are common in depression, but studies suggest that cognitive dysfunction is difficult to treat with antidepressants. Can adding an atypical antipsychotic medication to antidepressant treatment help lessen...
Nadia Iovieno, Richard C. Shelton, Samuel R. Petrie, et al
JCP
Original Research

May 24, 2017

When cultural stigma prevents Chinese Americans from seeking help for their MDD, can an ancient form of mind-body therapy improve their symptoms? Here, researchers investigate the effectiveness of tai...
Albert S. Yeung, Run Feng, Daniel Ju Hyung Kim, et al
JCP
Original Research

April 26, 2017

The atypical antipsychotic ziprasidone is effective in depressed patients who don' t respond to antidepressants, but is it safe? Learn about the clinical relevance of possible cardiac, metabolic, and...
David Mischoulon, Richard C. Shelton, Lee Baer, et al
JCP
Original Research

March 29, 2017

Adding an SNRI may improve impaired cognition and fatigue, and hence improve the overall depression outcome in patients with partial response to an SSRI. This analysis of trials of...
Virginia L. Stauffer, Peng Liu, Celine Goldberger, et al
JCP
Original Research

February 28, 2017

Depression is highly prevalent in patients with chronic pain. Mindfulness-based therapies show initial promise for both depression and chronic pain individually but have not been tested in patients with...
Marasha de Jong, Frenk Peeters, Tim Gard, et al
JCP
Original Research

December 28, 2016

Irritability and anger attacks affect about one-third of patients with major depressive disorder. This study by Fava et al evaluates adjunctive brexpiprazole as a strategy for patients with MDD...
Maurizio Fava, François Ménard, Charlotte Kampp Davidsen, et al
JCP
Original Research

October 26, 2016

Asian Americans have among the lowest rates of mental health service utilization of any racial/ethnic group in the United States, and research has identified stigma as an underlying reason...
Justin A. Chen, Benjamin G. Shapero, Nhi-Ha T. Trinh, et al
JCP
Original Research

August 24, 2016

T-CSCT for Depressed Chinese Americans
Albert Yeung, Max A. Martinson, Lee Baer, et al

Celebrating
85 Years

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