René S. Kahn, MD, PhD
Original Research
Generalizability of RCTs in First-Episode Schizophrenia
March 29, 2023
First-episode schizophrenia patients with suicidal ideation and substance use disorder are often excluded from clinical trials. Omitting them does not affect key outcome measures but excludes many potential subjects.
Original Research
Olanzapine/Samidorphan Mitigates Weight Gain in Early Illness
March 22, 2023
In patients with early-phase schizophrenia or bipolar disorder, combination olanzapine and samidorphan resulted in less weight gain at week 12 than olanzapine alone. Antipsychotic efficacy was similar between the...
