Original Research

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Recently published articles about Original Research

JCP
Mortality Within 1 Year After Suicide Attempt
Original Research

September 11, 2023

One in 100 people who attempted suicide died by suicide within 1 year; men aged 45 years or older were at greater risk than other demographic groups.
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JCP
Risk-Sensitive Decision-Making and Self-Harm
Original Research

September 6, 2023

Greater risk-taking has been associated with suicide attempts in youth with major depression. This study examined whether the association between self-harm and risk-sensitive decision-making is true for bipolar disorder...
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JCP
Safety and Efficacy of Aripiprazole 2-Month Ready-to-Use 960 mg
Original Research

September 4, 2023

A new formulation of injectable aripiprazole for administration every 2 months showed similar rates of treatment-emergent adverse events to aripiprazole once-monthly 400 mg. Patients in both groups remained clinically...
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PCC
Benztropine Usage Patterns in Movement Disorders
Original Research

August 29, 2023

This study evaluated real-world treatment patterns for patients initiating benztropine and examined treatment approaches in patients with drug-induced movement disorders from a health care provider perspective.
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JCP
Brexpiprazole in Patients With MDD and Prediabetes
Original Research

August 28, 2023

Some atypical antipsychotics, while efficacious as adjunctive treatments in major depressive disorder (MDD), can lead to adverse effects and weight gain. Adjunctive brexpiprazole had a limited impact on metabolic...
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JCP
Alcohol Use Disorder Treatment in Sexually and Gender Diverse Patients
Original Research

August 28, 2023

Sexually and gender diverse (SGD) patients had significantly higher rates of both AUD diagnosis and care utilization compared with non-SGD patients.
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JCP
Clozapine Delay and Schizophrenia Outcomes
Original Research

August 23, 2023

Clozapine is the drug of choice for treatment-resistant schizophrenia, but delays in initiation and underutilization may hinder its effectiveness. This study examined whether delay in clozapine initiation led to...
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JCP
Delirium and Mortality in COVID-19 Patients
Original Research

August 21, 2023

COVID-19 patients with early onset delirium had a 2-fold increased mortality risk—both in-hospital and after discharge—than those without delirium.
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JCP
Adjunctive Cariprazine for MDD With Inadequate Response to Antidepressants
Original Research

August 16, 2023

This study assessed the efficacy of adjunctive use of cariprazine, an atypical antipsychotic, in MDD patients with inadequate response to antidepressants.
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JCP
Fiscal Impact of Schizophrenia From a Government Perspective
Original Research

August 9, 2023

This analysis revealed that the lifetime fiscal loss to the government was $1,540,042 for each person with schizophrenia.
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JCP
Antihypertensive Medications and PTSD
Original Research

August 2, 2023

Calcium channel blockers were linked to decreased incidence of PTSD; the association was not found for any other antihypertensive medication classes.
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PCC
The NIMH Research Portfolio: An Update
Original Research

August 1, 2023

NIMH has continued to prioritize basic research over clinical trials, resulting in a decline in funding for possible treatments for psychiatric diseases.
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