Original Research

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Recently published articles about Original Research

JCP
Inhaled Mebufotenin (GH001) for Adult Patients with Postpartum Depression
Original Research

June 3, 2026

Mebufotenin (GH001) demonstrated rapid and significant improvements in depressive symptoms and remission of postpartum depression.
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PCC
Global Research Trends in Community Psychiatry
Original Research

June 2, 2026

This bibliometric analysis identifies the practice-relevant areas most emphasized in the “community psychiatry” literature (2015–2025), which clinicians can use to prioritize local quality improvement targets aligned with current service...
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JCP
Viloxazine ER in Adults With ADHD and Depression and/or Anxiety Symptoms
Original Research

May 27, 2026

Viloxazine ER was well tolerated and associated with improvements in ADHD, depression, and anxiety symptoms in this real-world study.
, , , et al
PCC
Lorazepam vs. Diazepam in AUD
Original Research

May 26, 2026

Both lorazepam and diazepam led to more than 50% reduction in Clinical Institute Withdrawal Assessment for Alcohol–Revised scores within 5 days of initiation of treatment in alcohol dependence syndrome.
, , , et al
JCP
National Trends in PTSD among US Military Veterans
Original Research

May 25, 2026

Compared with 2019–2020, past-month PTSD prevalence was higher among men, White and racial/ethnic minority veterans, and veterans aged 18–59 years
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JCP
Effect of a Nationwide Aftercare Program for Self-Harm Presentations on the Risk of Self-Harm Repetition and Suicide
Original Research

May 20, 2026

Aftercare following self-harm was associated with increased risk of repeat self-harm hospital presentation and decreased risk of suicide.
, , , et al
JCP
Differential Impact of Cholecystokinin and Ghrelin on 2-Year Avoidant/Restrictive Food Intake Disorder Symptoms
Original Research

May 20, 2026

Decreases in CCK and increases in ghrelin were associated with improvements in ARFID symptomology.
, , , et al
JCP
NNT, NNH, and LLH for Aripiprazole Once-Monthly in Schizophrenia
Original Research

May 13, 2026

Data demonstrate a favorable benefit-risk profile for aripiprazole once-monthly 400 vs placebo in acute and maintenance treatment of schizophrenia.
, , , et al
JCP
Efficacy and Safety of a Single Dose of Psilocybin for Chronic Suicidal Ideation
Original Research ▶ Video

May 13, 2026

A single psilocybin dose with psychological support was associated with rapid, large, and durable reductions in suicidal ideation and depressive symptoms.
, , , et al
JCP
Effects of Experimental Intermittent Theta Burst Stimulation on Negative Symptoms of Schizophrenia
Original Research

May 11, 2026

Findings suggest limited efficacy of experimental intermittent theta burst stimulation over the left DLPFC for negative symptoms.
, , , et al
PCC
Readability of Self-Reported Psychosis Measures
Original Research

May 5, 2026

Most psychosis self-report measures are written above recommended reading levels, reducing accessibility for many patients with cognitive, educational, or symptomatic limitations.
, , , et al
JCP
CBT following Esketamine for Major Depression and Suicidal Ideation for Relapse Prevention: The CBT-ENDURE Randomized Trial
Original Research

May 4, 2026

In patients with major depression and suicidal ideation, adding a 16-week CBT course to esketamine led to greater improvements in suicidal ideation and depression severity than esketamine alone.
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