Restless Legs Syndrome (RLS) is a neurological disorder causing an uncontrollable urge to move the legs. While primarily neurological, it can have psychiatric implications. The Journal of Clinical Psychiatry delves into the psychiatric aspects of RLS, from its impact on sleep and mood to therapeutic strategies. Our expert editors curate content that is actionable and comprehensive, aiding psychiatrists in understanding and managing the condition.
Restless Legs Syndrome
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Consensus Statement
Next-Step Treatment Options for Treatment-Resistant Depression
January 21, 2026
Strong consensus emerged for augmentation with second-generation antipsychotics, TMS, and ketamine/esketamine in the base vignette. Preferences shifted to include non-augmentative antidepressants and ECT based on patient characteristics.
