Meta-Analysis

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PCC
rTMS in Depression, Schizophrenia, and OCD
Meta-Analysis

September 26, 2023

In treatment-resistant depression, repetitive transcranial magnetic stimulation had higher odds of response and remission rates compared to sham.
Shweta Patel, Suraiya Silvi, Saral Desai, et al
JCP
Omega-3 PUFA Supplements for ADHD
Meta-Analysis

August 30, 2023

Although omega-3 polyunsaturated fatty acids (PUFAs) may not improve core symptoms of attention-deficit/hyperactivity disorder, longer-term PUFA supplementation may have potential benefits.
Ting-Hui Liu, Jheng-Yan Wu, Po-Yu Huang, et al
JCP
Mechanisms of Treatment of Bipolar Disorder and Borderline Personality Disorder: Brain Imaging Research
Meta-Analysis

March 27, 2023

Different brain regions were changed with psychotherapy versus medication. The findings may help with predicting treatment efficacy and identifying treatment biomarkers in these disorders.
Jingyi Luo, Meng Liang, Pengcheng Yi, et al
JCP
Antipsychotic Dose and Weight Gain
Meta-Analysis

February 8, 2023

Although effects on weight gain have been explored for several antipsychotics, the role of dose in producing these effects has not been widely studied. This meta-analysis examined the association...
Michel Sabé, Konstantinos Pallis, Marco Solmi, et al
JCP
Rapidity of Improvement With Intranasal Esketamine for MDD
Meta-Analysis

December 12, 2022

This meta-analysis found that augmenting antidepressants with intranasal esketamine vs placebo was more effective in reducing depression severity at 24 hours and study endpoint.
Rebecca S. Hock, Anna Feeney, Nadia Iovieno, et al
JCP
Tools to Detect Suicide Risk
Meta-Analysis

November 16, 2022

More than 20 instruments have been developed to assist in detecting suicide risk in adults. This systematic review used likelihood ratio analysis to determine the diagnostic accuracy of instruments...
Natalie B. Riblet, Sarah Matsunaga, Younji Lee, et al
JCP
Prevalence of Bipolar Disorder in Perinatal Women
Meta-Analysis

July 13, 2022

Perinatal women may be at increased risk for bipolar-spectrum mood episodes. This review and meta-analysis aimed to estimate overall prevalence of bipolar disorder and the prevalence and timing of...
Grace A. Masters, Julie Hugunin, Lulu Xu, et al
JCP
Telehealth vs Face-to-Face Management for PTSD in Primary Care
Meta-Analysis

May 23, 2022

This timely meta-analysis compared telehealth with face-to-face care for patients with PTSD, examining PTSD severity, QoL, therapeutic alliance, and other aspects.
Anna Mae Scott, Mina Bakhit, Hannah Greenwood, et al
JCP
Exclusion and Refusal in Youth Suicide Prevention RCTs
Meta-Analysis

February 15, 2022

Ineligibility for and refusal to take part in randomized controlled trials (RCTs) can make samples unrepresentative and limit generalizability of findings. This meta-analysis estimated the exclusion and refusal rates...
Ryoko Susukida, Masoumeh Amin-Esmaeili, Taylor C. Ryan, et al
JCP
Meta-Analysis

January 18, 2022

Psychedelic therapy shows promise for a range of mental health concerns, including suicidality. This meta-analysis is the first to systematically examine the effects of psychedelic therapy on suicidality.
Richard J. Zeifman, Dengdeng Yu, Nikhita Singhal, et al
JCP
Meta-Analysis

January 18, 2022

Repetitive magnetic transcranial stimulation (rTMS) has been established as an efficacious treatment for MDD. This meta-analysis looked at its effects on suicidal ideation in depressed patients across the lifespan.
Shobha Mehta, Gerasimos Konstantinou, Cory R. Weissman, et al
JCP
Meta-Analysis

December 28, 2021

This review synthesizes evidence on the efficacy of motivational interviewing in reducing substance use and psychotic symptoms.
Wenyue Wang, Anson Kai Chun Chau, Paul Kong, et al
JCP
Meta-Analysis

December 14, 2021

Increased screening for hepatitis C virus among people with serious mental illness is key to achieving global eradication of the virus.
Michael Rudi Braude, Timothy Phan, Anouk Dev, et al
JCP
Measurement-Based Care for Depression
Meta-Analysis

September 28, 2021

For patients with depressive disorders treated with pharmacotherapy, measurement-based care is effective in decreasing symptom severity, promoting remission, and improving medication adherence.
Maria Zhu, Ran Ha Hong, Tao Yang, et al
PCC
Meta-Analysis

June 24, 2021

Given the scarcity of data, the authors of this review systematically synthesized the literature to determine the long-term efficacy and safety of aripiprazole as a maintenance augmenting agent for...
Ashok Seshadri, Michaela E. Wermers, Timothy J. Habermann, et al
JCP
Meta-Analysis

June 15, 2021

Prior meta-analyses have found vortioxetine to be efficacious for depression. Building on those findings, the present meta-analysis examined the effect that placebo response has on drug-placebo effect size in...
Nadia Iovieno, George I. Papakostas, Anna Feeney, et al
JCP
Treatment of PTSD in Patients With Severe Mental Illness
Meta-Analysis

May 25, 2021

For patients who have PTSD and also have a severe mental illness, can psychotherapies for PTSD still be effective? If so, what component might offer greater efficacy?
Anouk L. Grubaugh, Wilson J. Brown, Jessica A. Wojtalik, et al
JCP
Meta-Analysis

May 4, 2021

This comprehensive meta-analysis informs clinicians and patients about the potential effectiveness of omega-3 fatty acids as add-on therapy for borderline personality disorder.
Dominika M. Karaszewska, Theo Ingenhoven, Roel J. T. Mocking
JCP
Meta-Analysis

February 23, 2021

Single-daily-dose regimens are easier for patients to follow than multiple-dose regimens and may increase adherence. But do they work as well? And are they safe? Read this meta-analysis to...
Yuhei Kikuchi, Yutaro Shimomura, Takefumi Suzuki, et al
JCP
Meta-Analysis

June 23, 2020

Women seem more likely than men to develop obsessive-compulsive disorder (OCD), but findings of individual studies are inconsistent. This meta-analysis estimated the worldwide prevalence of OCD to determine if...
Emily J. Fawcett, Hilary Power, Jonathan M. Fawcett
JCP
Meta-Analysis

June 9, 2020

Read a systematic review examining how antidepressant discontinuation affects the risk of depression relapse during pregnancy.
Hamideh Bayrampour, Arunima Kapoor, Mary Bunka, et al
JCP
Meta-Analysis

May 26, 2020

The FDA has now approved intranasal esketamine as augmention in treatment-resistant depression, and recent studies of its efficacy have been encouraging. This meta-analysis synthesizes the evidence to provide an...
George I. Papakostas, Naji C. Salloum, Rebecca S. Hock, et al
JCP
Meta-Analysis

May 26, 2020

Many augmentation agents have been examined regarding efficacy for antipsychotic-induced tardive dyskinesia (TD).The goal of this systematic review and meta-analysis was to examine the efficacy of these agents used...
Bekir B. Artukoglu, Fenghua Li, Natalia Szejko, et al
JCP
Meta-Analysis

May 26, 2020

First-line treatments for OCD include selective serotonin reuptake inhibitors and cognitive-behavioral therapy. But what do you do when patients do not respond to these or second-line strategies? In this...
Filipe Peste Martinho, Gonçalo Silva Duarte, Frederico Simões do Couto

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