Narrative Review

Narrative Review

Adjunctive Treatment Targeting Multiple Mechanisms in Schizophrenia

August 19, 2024

While the pathophysiology of schizophrenia is complex, treatments with novel pharmacological actions that target these systems are of interest as adjunctive treatment for schizophrenia.

Narrative Review

Management of ADHD in Adolescents and Young Adults

August 6, 2024

Drawing on their clinical experiences of implementing evidence-based guidelines and feedback from patients, the authors describe innovative strategies and solutions for improving the management of ADHD in adolescents and...

Narrative Review

Tech Gaming Designs, Neurodevelopmental Vulnerabilities, and Internet Gaming Disorder Risk

July 23, 2024

The authors review the relevant research in the field of internet gaming disorder and provide an approach to identification and management.

Narrative Review

Immune Targeted Therapies for Depression: Antidepressant Effects of Monoclonal Antibodies

June 24, 2024

Immune dysregulation may contribute to treatment resistance in depression. Monoclonal antibodies have shown promise in treating depression when used for inflammatory disorders and may offer new hope for patients...

Narrative Review

Alternative Treatment for Agitation in Schizophrenia and Bipolar Disorder

January 30, 2024

While oral and intramuscular formulations of pharmacologic agents continue to be commonly used to treat acute agitation, novel agents with alternative routes of delivery are becoming available.

Narrative Review

Neuropsychiatric Manifestations and Management of Tuberous Sclerosis

January 4, 2024

Ninety percent of individuals with tuberous sclerosis have associated neuropsychiatric manifestations including ADHD, autism spectrum disorder, and intellectual disability, which are typically underidentified and undertreated.

Narrative Review

Fentanyl-Contaminated Oxycodone

November 9, 2023

The growing use of fentanyl-contaminated products is fueling the US opioid crisis. This study reviewed the rising prevalence of nonprescription fentanyl in counterfeit oxycodone, paying specific attention to oxycodone...

Narrative Review

Xylazine as a Fentanyl Adulterant in the US

October 31, 2023

Data obtained from studies between 2006 and 2022 indicate a rapidly increasing incidence of xylazine overdose in the United States, with overdose cases now being seen in 25 states.

Narrative Review

Eating Disorders and Reproductive Health

August 31, 2023

Recognition and treatment of eating disorders in women prior to conception can minimize obstetric risks to the woman and potential long-term adverse effects on the offspring.

Narrative Review

Wernicke’s Encephalopathy in Patients With Psychiatric History

July 20, 2023

Wernicke’s encephalopathy can present concomitantly with psychiatric decompensation, often requiring treatment with both neuroleptics and thiamine.

Narrative Review

L-Methylfolate as Adjunctive Therapy in MDD Treatment

May 9, 2023

l-Methylfolate is effective as an adjunctive treatment in MDD and may especially benefit patients with higher body mass index and inflammation.

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Narrative Review

Collaborative Care Model Education Opportunities

April 25, 2023

The Collaborative Care Model (CoCM) is an evidence-based methodology to improve access to mental health care, but studies on how CoCM is taught are sparse. Future opportunities abound to...

Narrative Review

Repurposing Psychiatric Drugs

March 20, 2023

Drugs labeled as “psychotropic” often have widespread reach and impact throughout the brain and body. Thus, many of these drugs could be repurposed for non-psychiatric indications of high public...

Narrative Review

Management of Psychiatric Conditions in POTS

January 31, 2023

This review provides an evidence-based approach to treating common psychiatric conditions in those who suffer from POTS, with a particular emphasis on side effects that may worsen the associated...

Narrative Review

Managing Insomnia in Primary Care

January 24, 2023

This review provides up-to-date guidance on the management of insomnia disorder for primary care providers and describes gaps in current recognition and treatment.

Narrative Review

Postpartum Psychosis or Something Else?

January 5, 2023

A case of postpartum psychosis with malignant catatonia highlights the role of immunology in the development and treatment of postpartum psychosis.

Narrative Review

Gastrointestinal Symptoms and Psychosis

June 23, 2022

There are numerous clinical scenarios in which gastrointestinal and psychotic symptoms commonly co-occur; thus, it is important that both psychiatrists and primary care physicians have a familiarity with the...

Narrative Review

miRNAs and Impact on Schizophrenia Management

April 7, 2022

This review summarizes the most important findings of experimental investigations aimed at identifying the role of human miRNAs in schizophrenia management, as well as the expression of different miRNAs...

Narrative Review

Hallucinations and Delusions With Dementia in LTC

March 7, 2022

This narrative review addresses barriers to diagnosing dementia-related psychosis, outlines the prevalence and presentation of psychosis among dementia types, and reviews current practices for treating dementia-related psychosis in long-term...

Narrative Review

Neuropsychiatric Symptoms of Autoimmune Encephalitis

February 15, 2022

This review and case series of 7 patients highlights the variable presentations of autoimmune encephalitis in order to help physicians better recognize it in patients with mixed neuropsychiatric symptoms.

Narrative Review

Caring for Adults With Eating Disorders in Primary Care

January 6, 2022

Here, read the most up-to-date screening and treatment guidelines and relevant studies concerning the care of adult patients with eating disorders, including concise guidance regarding the outpatient management of...