Original Research

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Posts about this type

JCP
Original Research

December 4, 2018

Nonsteroidal anti-inflammatory drugs (NSAIDs) and antioxidative treatments have shown antidepressant potential as adjunct treatments. Read this article to learn if adjunctive treatment with the antioxidative agent N-acetylcysteine, the NSAID...
Isabelle E. Bauer, Charles Green, Gabriela D. Colpo, et al
JCP
Original Research

December 4, 2018

Poor treatment adherence masks the true extent of placebo effects in trials of antipsychotics in schizophrenia. Can use of an injectable placebo in double-blind trials of long-acting injectable antipsychotics...
Fumiaki Kumagai, Takefumi Suzuki, W. Wolfgang Fleischhacker, et al
JCP
Original Research

December 4, 2018

If a patient's depressive symptoms subside very quickly after antidepressant treatment is initiated, do those gains represent a true and lasting response? This study examined whether sudden improvement in...
Sigal Zilcha-Mano, Steven P. Roose, Patrick J. Brown, et al
JCP
Original Research

November 27, 2018

Which subgroups of patients with schizophrenia or schizoaffective disorder may be prone to treatment failure? Is it men or women, old or young, or are more factors involved? Researchers...
T. Scott Stroup, Natalie A. Bareis, Robert A. Rosenheck, et al
JCP
Original Research

November 27, 2018

Depression in older adults is associated with a greater risk of dementia as well as mild cognitive impairment (MCI). This study aimed to identify possible risk factors for developing...
Damien Gallagher, Alex Kiss, Krista L. Lanctôt, et al
JCP
Original Research

November 20, 2018

A suicide expert shares in her interview on suicide prevention that she had been in suicidal crisis at one point in her life. Do you think subjects in this...
Benedikt Till, Florian Arendt, Sebastian Scherr, et al
JCP
Original Research

November 20, 2018

In your patients with MDD, cognitive deficits may have a greater impact than you realize. This study used the THINC-it assessment to determine the extent to which impaired cognition...
Matthew J. Knight, Célia Fourrier, Ellen Lyrtzis, et al
JCP
Original Research

November 13, 2018

Depression is strongly associated with functional impairment. Some hypothesize that cognitive dysfunction, which is also often associated with depression, might mediate the impact of depression on functioning. This study...
Hélène Vulser, Emmanuel Wiernik, Nicolas Hoertel, et al
JCP
Original Research

November 13, 2018

Frailty is associated with negative health outcomes in dementia patients, but could it also predict more psychological symptoms and greater caregiver burden? This study of 1,193 Alzheimer's disease patients...
Taiki Sugimoto, Rei Ono, Ai Kimura, et al
JCP
Original Research

November 6, 2018

Emergency departments are often the first point of care for youth with psychosis. Timely follow-up care is crucial, but how often is it received? This retrospective study looks at...
Nicole Kozloff, Binu Jacob, Aristotle N. Voineskos, et al
JCP
Original Research

November 6, 2018

Do you know the method preferred by your suicidal patients when they attempt suicide? Among nearly 28,000 suicide attempters, a third used a psychotropic medication. Find out which populations...
Talia L. Brown, Peter M. Gutierrez, Gary K. Grunwald, et al
JCP
Original Research

October 30, 2018

Regular cannabis use during adolescence has been linked to cognitive impairments. To what degree does abstaining from cannabis lead to cognitive improvements in adolescents and young adults who otherwise...
Randi Melissa Schuster, Jodi Gilman, David Schoenfeld, et al
JCP
Original Research

October 23, 2018

Could cerebrovascular disease be a factor in your elderly patient's depression? This article investigated the association of white matter hyperintensities and cerebral blood flow with late-life depressive symptoms and...
Wenjing Wei, Helmet T. Karim, Chemin Lin, et al
JCP
Original Research

October 23, 2018

Are heavy drinkers more likely to die by suicide at a particular time of the day? This study used a large database to examine circadian peaks and nadirs in...
Subhajit Chakravorty, Rachel V. Smith, Michael L. Perlis, et al
JCP
Original Research

October 23, 2018

Although benzodiazepines can provide short-term relief for anxiety, their potential to worsen depression and suicidal thoughts potentially recommends against their use in patients with PTSD. Read this article to...
Rishi Deka, Craig J. Bryan, Joanne LaFleur, et al
JCP
Original Research

October 16, 2018

Benzodiazepines are used widely for anxiety and insomnia, but what proportion of users are misusing them? This analysis of National Surveys on Drug Use and Health data considers correlates...
Carlos Blanco, Beth Han, Christopher M. Jones, et al
JCP
Original Research

October 16, 2018

The consequences of neurologic injury in early childhood can be profound and long-lasting. This analysis of data from a Taiwanese national insurance database examines the association between TBI in...
Hsuan-Kan Chang, Ju-Wei Hsu, Jau-Ching Wu, et al
JCP
Original Research

October 9, 2018

Psychiatric disorders often co-occur, and comorbidity patterns as well as suicide risk vary across the lifespan. Read this article to learn if suicide attempt risk in older and younger...
Rachel Pascal de Raykeer, Nicolas Hoertel, Carlos Blanco, et al
JCP
Original Research

October 9, 2018

In the search for a cause of obsessive-compulsive disorder, 2 theories have predominated: increased activity in the orbitofrontal cortex and low activity in the serotonergic system. Using fMRI and...
Paraskevi Mavrogiorgou, Björn Enzi, Saskia Steinmann, et al
JCP
Original Research

October 2, 2018

Tobacco has known associations with psychosis, but less is known about the relationship between tobacco use and subclinical psychotic-like experiences (PLEs). This study sought to disentangle the association of...
Jasmina Mallet, Nicolas Mazer, Caroline Dubertret, et al
JCP
Original Research

October 2, 2018

People who have received inpatient psychiatric care are at greater risk of dying an unnatural death. This study, which drew on data from persons born in Denmark from 1967-1996,...
Florian Walter, Matthew J. Carr, Pearl L. H. Mok, et al
JCP
Original Research

September 25, 2018

Once a patient is discharged after a suicide attempt, what can be done to prevent another attempt? This study evaluated a suicide prevention strategy algorithm versus treatment as usual...
Guillaume Vaiva, Sofian Berrouiguet, Michel Walter, et al
JCP
Original Research

September 25, 2018

Treatment nonadherence is bipolar disorder ranges from 20% to 60%. Read this article to learn how customized adherence enhancement (CAE)—a brief, bipolar disorder-specific approach that targets individual adherence barriers—compared...
Martha Sajatovic, Curtis Tatsuoka, Kristin A. Cassidy, et al
JCP
Original Research

September 25, 2018

Polypharmacy has been shown to be associated with dementia, though its relationship to mild cognitive impairment (MCI), often a precursor to dementia, has received less study. Read this article...
Chih-Ming Cheng, Wen-Han Chang, Yu-Chuan Chiu, et al

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