Original Research

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Posts about this type

JCP
Original Research

August 23, 2017

Is vitamin D supplementation beneficial in treating cognitive impairments in psychotic disorders? Read this cross-sectional study to discover which cognitive deficits were associated with vitamin D deficiency.
Mari Nerhus, Akiah O. Berg, Carmen Simonsen, et al
JCP
Original Research

August 22, 2017

Is bone mineral density related to severity of current symptoms of depression? Read this article to learn if this hitherto-unresolved connection exists.
Rocco D. Hlis, Roger S. McIntyre, Naim M. Maalouf, et al
JCP
Original Research

August 15, 2017

Functional impairment often persists after the remission of an anxiety disorder. Read this article to learn whether this impairment reflects a continuation of lower functioning that predated the illness,...
Simone M. E. Schopman, Margreet ten Have, Saskia van Dorsselaer, et al
JCP
Original Research

August 8, 2017

Depression occurs in nearly 22% of new mothers within the year after the birth. Telephone care management could offer a flexible and efficient way to reach out to these...
Katherine L. Wisner, Dorothy K. Y. Sit, Mary McShea, et al
JCP
Original Research

August 1, 2017

Could mood-stabilizing medications be increasing patients' risk of developing kidney disease? This large, nested case-control study looks at the degree of risk associated with lithium and valproate treatment in...
Soham Rej, Nathan Herrmann, Kenneth Shulman, et al
JCP
Original Research

August 1, 2017

Delirium can be a very disturbing, and often stigmatizing, experience. This placebo-controlled study, set in intensive care units and acute wards, investigates administration of suvorexant near the time of...
Kotaro Hatta, Yasuhiro Kishi, Ken Wada, et al
JCP
Original Research

July 25, 2017

What if an objective physical marker of depression severity could be identified? Read this article to see the relationships found between severity of depression and levels of monoamine metabolites...
Hyung Shin Yoon, Kotaro Hattori, Shintaro Ogawa, et al
JCP
Original Research

July 25, 2017

Could you correctly diagnose a patient with behavioral variant frontotemporal dementia? This original research article compares the clinical presentation of this disorder with those of psychiatric disorders such as...
Everard G. B. Vijverberg, Sigfried Schouws, Paul David Meesters, et al
JCP
Original Research

July 25, 2017

Cognitive deficits are common in depression, but studies suggest that cognitive dysfunction is difficult to treat with antidepressants. Can adding an atypical antipsychotic medication to antidepressant treatment help lessen...
Nadia Iovieno, Richard C. Shelton, Samuel R. Petrie, et al
JCP
Original Research

July 18, 2017

In 2015, the FDA removed WBC monitoring altogether and reduced the threshold for ANCs before interruption of clozapine treatment was required. The current study looks at almost 250 clozapine-treated...
Ryan S. Sultan, Mark Olfson, Christoph U. Correll, et al
JCP
Original Research

July 11, 2017

Read a study discussing the possibility of early pharmacotherapeutic treatment being able to prevent PTSD.
Joseph Zohar, Leah Fostick, Alzabeta Juven-Wetzler, et al
JCP
Original Research

July 11, 2017

Although psychoeducation can benefit patients with borderline personality disorder, the lack of trained personnel and the cost of implementation have prevented widespread adoption of this treatment. Read this article...
Mary C. Zanarini, Lindsey C. Conkey, Christina M. Temes, et al
JCP
Original Research

July 11, 2017

Quetiapine has the greatest evidence of efficacy for bipolar II depression, but it is also associated with metabolic side effects. This study compared psychotherapy plus placebo or plus pharmacotherapy....
Holly A. Swartz, Paola Rucci, Michael E. Thase, et al
JCP
Original Research

July 5, 2017

Antipsychotic medications are increasingly prescribed to treat depression. But is this use always warranted? Read the article by Gerhard and colleagues to learn how often antipsychotics are prescribed in...
Tobias Gerhard, T. Scott Stroup, Christoph U. Correll, et al
JCP
Original Research

June 28, 2017

Are female patients who are taking prolactin-elevating antipsychotics at increased risk for uterine cancer? The authors of this population-based cohort evaluated the evidence in a 24-year period for nearly...
Adi J. Klil-Drori, Hui Yin, Haim A. Abenhaim, et al
JCP
Original Research

June 28, 2017

Read a study on the relationship between aggression and substance use, and whether aggression was a risk factor for substance use.
Emil F. Coccaro, Jennifer R. Fanning, Royce Lee
JCP
Original Research

June 28, 2017

Both long-term and acute substance use can play a role in suicidal behavior, though most research to date has focused on the former. Read this article to learn which...
Courtney L. Bagge, Guilherme Borges
JCP
Original Research

June 20, 2017

Is there a way to reduce the abuse potential of stimulant medications while retaining their effectiveness in treating ADHD? Read this article by Spencer and colleagues to learn the...
Thomas J. Spencer, Pradeep Bhide, Jinmin Zhu, et al
JCP
Original Research

May 24, 2017

Anticonvulsants are often prescribed to veterans with PTSD, but how certain are we that these agents are effective for this indication? Read this analysis of medical records from the...
Brian Shiner, Christine Leonard Westgate, Nancy C. Bernardy, et al
JCP
Original Research

May 24, 2017

Apathy is increasingly prevalent as individuals age. Read this article to explore the relationship between apathy and markers of functional decline—specifically, slow gait, frailty, and disability—in older community-dwelling adults.
Emmeline Ayers, Miriam Shapiro, Roee Holtzer, et al
JCP
Original Research

May 24, 2017

Could cadmium and lead, toxic metals present in tobacco smoke, be major contributors to the link between tobacco smoke and depression? This study draws on data from the National...
Melanie C. Buser, Franco Scinicariello
JCP
Original Research

May 24, 2017

When cultural stigma prevents Chinese Americans from seeking help for their MDD, can an ancient form of mind-body therapy improve their symptoms? Here, researchers investigate the effectiveness of tai...
Albert S. Yeung, Run Feng, Daniel Ju Hyung Kim, et al
JCP
Original Research

May 24, 2017

Cortisol and the role of the hypothalamic-pituitary-adrenal axis are important in the development and treatment of PTSD. This study probed the association between HPA axis reactivity and treatment response...
Sheila A. M. Rauch, Anthony P. King, Israel Liberzon, et al
JCP
Original Research

May 24, 2017

Cortical-subcortical imbalance could be a trait-related pathogenic factor of bipolar disorder. Find out if the purported cortical-subcortical dissociation was detected by degree centrality, a robust index of focal connectivity...
Qian Zhou, Fay Y. Womer, Lingtao Kong, et al

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