Original Research

JCP
Original Research

August 28, 2018

Attention-deficit/hyperactivity disorder may be a precursor to oppositional defiant disorder and conduct disorder. Could better adherence to medication treatment for ADHD lower the chance that youths will later develop...
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JCP
Original Research

August 28, 2018

Telehealth, or treating patients remotely via communications technology, is demonstrably effective and is an appealing option for many reasons, but is it cost-effective? This study of older veterans compared...
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JCP
Original Research

August 28, 2018

Older people with major depressive disorder often don' t respond to antidepressants and may experience greater cognitive dysfunction. Could nicotine patches help? This 12-week open study in 15 nonsmoking...
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JCP
Original Research

August 21, 2018

Vagus nerve stimulation (VNS) treatment has been shown to be efficacious in treatment-resistant depression (TRD). Can VNS treatment lead to improvements in quality of life in patients with TRD...
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JCP
Original Research

August 14, 2018

Each year in the US, millions of people misuse prescription opioids. To combat this, it's important to understand the motivations. This analysis of data from the National Survey on...
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JCP
Original Research

August 14, 2018

Although smoking prevalence in the US has declined overall, is it declining among those with mental illness and substance use problems? These authors drew from the National Survey on...
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JCP
Original Research

August 7, 2018

As you probably know, sexual dysfunction is a common side effect of antidepressants and antipsychotics. This secondary analysis of an RCT examines whether the atypical antipsychotic lurasidone was linked...
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JCP
Original Research

August 7, 2018

ADHD symptoms tend to emerge over time, meaning that some children will manifest subsyndromal symptoms of ADHD before they meet full diagnostic criteria. Read this article to learn how...
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JCP
Original Research

July 31, 2018

Many individual factors influence risk of suicide attempt. How can these disparate factors be understood in light of each other? Read this article to learn about a comprehensive model...
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JCP
Original Research

July 24, 2018

Appetitive symptoms predict response to bright light therapy in patients with seasonal depression.  Are these symptoms also predictive of response to light therapy in nonseasonal depression? Read this article...
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JCP
Original Research

July 24, 2018

Ketamine, an off-label treatment for depression, can have rapid-acting antidepressant effects but is also sometimes associated with negative clinical outcomes. Do the short- and long-term benefits of ketamine treatment...
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JCP
Original Research

July 24, 2018

Although chronic schizophrenia has been linked to elevated rates of suicide, data on suicide rates in first-episode schizophrenia are scarce. Read this article to learn the rate of suicide...
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JCP
Original Research

July 18, 2018

Could electroconvulsive therapy have beneficial effects on sleep? This study looked at combination therapy with venlafaxine and ECT in a depressed elderly population—read the article to see whether ECT...
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JCP
Original Research

July 10, 2018

Identifying individuals likely to progress from suicidal thoughts to action is a major target in suicide prevention. Read this article to learn the practical value that intrinsic brain organization...
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JCP
Original Research

July 10, 2018

Many adolescents with mental disorders do not receive specialist treatment, and those who do often wait several years before beginning treatment. Do parents, teachers, or the adolescents themselves have...
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JCP
Original Research

July 10, 2018

Read a study on how a extract of Ashwagandha (Withania somnifera), when added to antipsychotic medications to patients with schizophrenia.
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JCP
Original Research

July 3, 2018

What factors lead to poor mental health in teens? These authors used a baseline survey and then a follow-up survey to evaluate lifestyle and social characteristics that predicted deterioration...
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JCP
Original Research

July 3, 2018

Read a randomized control trial evaluating tianeptine's efficacy in patients 65 and older with recurrent major depressive disorder (MDD).
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JCP
Original Research

June 26, 2018

Reports on the efficacy of omega-3 fatty acids for depression are mixed, with only limited data in adolescents.  This RCT compared their efficacy versus placebo in 51 adolescents with...
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JCP
Original Research

June 26, 2018

Clinical Practice Guidelines have been published by the US military to aid in clinical management of patients with PTSD. To investigate whether these best-practice guidelines are being followed, this...
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JCP
Original Research

June 19, 2018

Augmentation of antidepressants with aripiprazole is effective in treating late-life depression. As an antipsychotic medication, however, aripiprazole potentially leads to extrapyramidal side effects (EPS). Read this article to learn...
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JCP
Original Research

June 19, 2018

High rates of schizophrenia symptom recurrence after antipsychotic treatment discontinuation are are thought to be due to withdrawal-related phenomena rather than illness recurrence. This post hoc analysis examines results...
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JCP
Original Research

June 12, 2018

Individuals with depression can experience diminished levels of reward positivity (RewP), a neurophysiologic index of reward responsiveness. Can changing levels of RewP be used as an objective index of...
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JCP
Original Research

May 29, 2018

Treatment-resistant depression (TRD), broadly defined, is depression not in remission after treatment. About a third of depressed patients lack response to at least one adequate treatment. But how can...
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Consensus Report on XT Use in Practice

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Figure: Graphic promoting Consensus Report on Xanomeline-Trospium; colorful net design shown with JCP logo in lower left.

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