Original Research

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PCC
REL-1017 Effects on Cognition in MDD
Original Research

February 14, 2023

REL-1017 improved subjective measures of cognitive impairment, in addition to improving total MADRS and SDQ scores.
Clotilde Guidetti, Giulia Serra, Luca Pani, et al
JCP
Predictors for Initiation of LAIs in Individuals With Early-Phase Schizophrenia
Original Research

February 13, 2023

Initiation of LAIs was predicted by greater switching of oral antipsychotics and more ED visits. LAIs are often used to respond to relapse rather than prevent it.
Jose M. Rubio, Marko A. Mychaskiw, Sangtaeck Lim, et al
PCC
Influence of Religion on Physicians’ Attitudes Toward Homosexuality
Original Research

February 9, 2023

Attitudes overall were positive toward homosexuality; however, those belonging to Abrahamic religions, especially Muslims, had more negative attitudes.
Bishurul Hafi, N. A. Uvais, Salin K. Eliyas, et al
JCP
Ketamine vs Esketamine for TRD
Original Research

February 1, 2023

Are ketamine and esketamine equally efficacious? This observational study compares the efficacy of subanesthetic intravenous ketamine with that of intranasal esketamine for treatment-resistant depression in a real-world clinical setting.
Balwinder Singh, Simon Kung, Vanessa Pazdernik, et al
JCP
Effect of Zuranolone on Anxiety and Insomnia in Postpartum Depression
Original Research

January 30, 2023

Zuranolone was associated with improvements in depressive and anxiety symptoms and was beneficial for insomnia and patient-perceived functional health in patients with PPD.
Kristina M. Deligiannidis, Leslie Citrome, Ming-Yi Huang, et al
JCP
Young-Adult Social Outcomes of ADHD
Original Research

January 25, 2023

ADHD that persisted into young-adulthood was associated with poorer outcomes in terms of education, employment, and emotional support.
Lucy Riglin, Andrew Todd, Rachel Blakey, et al
JCP
Effects of ECT in Comorbid Depression and Dementia
Original Research

January 25, 2023

Limited data suggest a role for electroconvulsive therapy (ECT) in treating behavioral and psychological symptoms of dementia. Using a larger sample size than in previous reports, this study examined...
Samuel T. Wilkinson, Kyaw Sint, Brent P. Forester, et al
PCC
Computer Vision Syndrome and Mental Health
Original Research

January 19, 2023

In this study, computer vision syndrome was associated with depression, anxiety, and insomnia.
Georges Merhy, Marwan Akel, Nelly Kheir, et al
PCC
PTSD and Child Sexual Abuse
Original Research

January 17, 2023

This study found an association between PTSD and history of sexual abuse and higher prevalence of MDD and substance use disorder, which can ultimately increase the risk of suicide.
Pranita Mainali, Fatima Motiwala, Chintan Trivedi, et al
JCP
Atomoxetine and Prevalence of Major Congenital Malformations
Original Research

image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ January 16, 2023

Little is known about the safety of atomoxetine, a non-stimulant treatment for attention-deficit/hyperactivity disorder. This study assessed the prevalence of major congenital malformations after first-trimester exposure to atomoxetine.
Gabriella Bröms, Sonia Hernández-Díaz, Krista F. Huybrechts, et al
JCP
Community Navigation Service for People With Serious Mental Illness
Original Research

January 16, 2023

Opening Doors to Recovery, a recovery support model, led to fewer days hospitalized, fewer arrests, and greater satisfaction with housing.
Michael T. Compton, Mary E. Kelley, Simone Anderson, et al
JCP
TMS in Anxious Depression
Original Research

January 11, 2023

Patients with anxious depression tend to have more severe depressive symptoms. This study examined the effects of transcranial magnetic stimulation in these patients.
Todd M. Hutton, Scott T. Aaronson, Linda L. Carpenter, et al
JCP
Risk of PNAS in SGA-Exposed Infants
Original Research

January 4, 2023

Roughly 30% of infants exposed to SGAs in utero exhibited poor neonatal adaptation syndrome; the percentage among antidepressant-exposed infants was similar.
Adele C. Viguera, Sara A. McElheny, Phoebe S. Caplin, et al
JCP
Prescription Stimulant Misuse Among US College Students
Original Research

December 28, 2022

Preventing and identifying prescription stimulant misuse (PSM) requires an understanding of risk factors and correlates, but large-scale surveys are lacking. This multi-institution study is the largest to date on...
Sylvia H. M. Wong, Courtney Stevens, Cindy H. Liu, et al
JCP
Primary Care–Based Mindfulness Training for PTSD in Veterans
Original Research

December 28, 2022

Four 90-minute mindfulness classes reduced psychiatric symptoms and improved health responsibility and stress management.
Kyle Possemato, Dessa Bergen-Cico, Katherine Buckheit, et al
PCC
Violent Video Games and Adolescents
Original Research

December 22, 2022

This study evaluated the association of different attachment styles with violent video game use among Lebanese male adolescents.
Marwan Akel, Jana Berro, Diana Malaeb, et al
JCP
Sleep Complaints and Risk of Psychiatric Disorders
Original Research

December 21, 2022

Sleep complaints were associated with risk of psychiatric disorders independent of sociodemographic and clinical characteristics in this study of NESARC data.
Bénédicte Barbotin, Nicolas Hoertel, Mark Olfson, et al
JCP
Video Intervention to Reduce Stigma: Gender Effects
Original Research

December 19, 2022

A video to reduce stigma against schizophrenia was more effective in women if the female narrator specifically referred to her gender than if she did not.
Doron Amsalem, Samantha E. Jankowski, Shannon Pagdon, et al
PCC
Psychiatric Disorders in Hospitalized Homeless Individuals
Original Research

December 15, 2022

This study revealed a positive association between homelessness, comorbid psychiatric disorders, and suicidal ideations/attempts.
Chintan Trivedi, Mahwish Adnan, Kaushal Shah, et al
JCP
Comparison of Catatonia Risk of 30 Antipsychotics
Original Research

December 14, 2022

In this postmarketing study, first-generation antipsychotics were associated with a greater risk of catatonia syndromes compared to second-generation antipsychotics.
Julien Da Costa, Etienne Very, Vanessa Rousseau, et al
JCP
Six-Month Follow-Up of Patients at Risk of Suicide Using Smartphone Data and Clinical Assessment
Original Research

December 14, 2022

Ecological momentary assessment (EMA) is increasingly used to detect suicidal ideation in real time. This study combined EMA with traditional clinical follow-up to explore correlates of suicidal relapse in...
Alejandro Porras-Segovia, Manon Moreno, María Luisa Barrigón, et al
PCC
Personality Traits and Online Pornography Use
Original Research

December 13, 2022

The study highlights that some personality traits, such as agreeableness and extroversion, and other factors, such as alcohol consumption, gender, and education level, are associated with online pornography use.
Elsa Sfeir, Diana Malaeb, Souheil Hallit, et al
JCP
Imminent Risk of Suicide Death in Psychiatric Patients
Original Research

image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ December 12, 2022

Efforts to identify short-term suicide risk have been hampered by methodological challenges. This large study prospectively investigated the predictive value of diagnosis, suicidal behavior, and depressed mood for imminent...
Kristin Joerstad Fredriksen, Christoffer Bartz-Johannessen, Helle Kristine Schoeyen, et al
JCP
Factors Associated With Posttraumatic Stress After COVID-19 Hospitalization
Original Research

December 7, 2022

Patients hospitalized with COVID-19 showed persistent posttraumatic stress symptoms 6 months later. These symptoms were linked to dissociative experiences while hospitalized and longer distances between home and the hospital.
Victor Pitron, Willys Cantenys, Anne Herbelin, et al

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