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PCC
hs-CRP as a Biomarker and Endophenotype in Mania
Original Research

December 6, 2022

Blood hs-CRP level is a biomarker in mania and may be a newer approach to detect disease progression and guide novel therapies.
Mohamed Abshad, Basudeb Das, Mahesh Kumar, et al
JCP
Pharmacotherapy After CBT in Anxious Youth
Original Research

December 5, 2022

This study of youth with anxiety disorders compared cognitive-behavioral therapy (CBT) non-remitters who initiated pharmacotherapy to those who did not and sought to identify predictors of the decision to...
Jeffrey R. Strawn, Jeffrey A. Mills, Richard Rothenberg, et al
JCP
Social Support and Suicidal Thoughts and Behaviors
Original Research

December 5, 2022

Greater diversity of social networks was more strongly associated with lower risks of suicidal thoughts and behaviors than perceived strength of social support.
Peter Jongho Na, Tanner Bommersbach, Robert H. Pietrzak, et al
JCP
Telehealth of CSC in Early Psychosis During COVID-19
Original Research

November 30, 2022

As the COVID-19 pandemic emerged in 2020, access to in-person clinical care was restricted. This study explored if transition of coordinated specialty care to telehealth for psychosis patients allowed...
Elisa B. Nelson, Olivia H. Franco, Bridgette A. Patton, et al
PCC
Pharmacist-Led Dementia Care Rounds and Sleep Medication Use
Original Research

November 29, 2022

Pharmacist-led dementia care rounds are an efficient way to correct sleep medication use and can contribute to benzodiazepine discontinuation, which is especially important in the elderly.
Koki Mori, Mitsuyo Yoshida, Kenji Tomita, et al
PCC
High-Dose Therapy in Treatment-Refractory Psychosis
Original Research

November 24, 2022

In forensic patients hospitalized in a long-term psychiatric facility, antipsychotic dose reduction had a positive effect on treatment effectiveness, competency restoration, and hospital discharge with no symptom relapse.
Mujeeb U. Shad
PCC
Therapeutic Dilemma of Wake-up Stroke
Original Research

November 24, 2022

The importance of recognizing wake-up stroke for early referral to acute stroke care is highlighted in this study, as patients may benefit from acute reperfusion therapy after obtaining the...
Erum Mubashir Shariff, Fahd Ali Al Khmais, Saima Nazish, et al
JCP
Bad Dreams and Nightmares Preceding Suicidal Behaviors
Original Research

November 23, 2022

Suicidal behavior may be preceded by a sequence of altered dreams that goes from bad dreams to nightmares and finally to suicidal scenarios in dreams a few weeks before...
Pierre A. Geoffroy, Rodolphe Borand, Marine Ambar Akkaoui, et al
PCC
Impairment of Sexual Desire in Treatment-Resistant Depression
Original Research

November 22, 2022

Patients with treatment-resistant depression had a high prevalence of sexual desire impairment, which was associated with male sex and higher depressive symptom severity.
Walter dos Santos Gonçalves, Roseane Dorte Halkjaer Lassen, Aline Sardinha, et al
JCP
Measuring Executive Function in ADHD With the BRIEF-A
Original Research

November 21, 2022

The BRIEF-A identified executive function deficits in adults with ADHD that added disability beyond that associated with ADHD alone.
Joseph Biederman, Maura L. DiSalvo, Chloe R. Hutt Vater, et al
JCP
Effect of Benzodiazepines on Antidepressant Effects of Ketamine
Original Research

November 14, 2022

Findings of studies examining the impact of benzodiazepines on antidepressant effects of ketamine are contradictory. This study assessed whether concomitant oral benzodiazepines differentially affected treatment response to ketamine versus...
Anna Feeney, Bettina B. Hoeppner, Marlene P. Freeman, et al
PCC
Boredom, Loneliness, and Smartphone Addiction Among Young Adults
Original Research

November 8, 2022

In this study, smartphone addiction was significantly associated with higher boredom proneness, anxiety, and loneliness.
Diana Malaeb, Marwan Akel, Pascale Salameh, et al
JCP
Suvorexant and Lemborexant for Prevention of Delirium
Original Research

November 7, 2022

The novel dual orexin receptor antagonists (DORAs) suvorexant and lemborexant may be helpful in preventing delirium. This study examined the efficacy of these two DORAs in preventing delirium in...
Ayaka Matsuoka, Shuko Tobita, Rintaro Sogawa, et al
JCP
Relationship Between bvFTD and Psychiatric Disorders
Original Research

November 2, 2022

The behavioral variant of frontotemporal dementia (bvFTD) overlaps with primary psychiatric disorders (PPD). This study compared family history of PPD in patients with bvFTD, healthy controls, and patients with...
Siham Icho, Nicole Korten, Lianne Reus, et al
PCC
History of Suicide Attempt and Clozapine in Veterans With Schizophrenia
Original Research

November 1, 2022

This study evaluated whether a history of suicide attempt increases the odds of receiving clozapine treatment in veterans with schizophrenia or schizoaffective disorder.
Gregory H. Jones, Brian G. Mitchell, Jared Bernard, et al
JCP
Psychotropic Use in Youth With MDD and ADHD
Original Research

October 31, 2022

Data from a 17-year study point to overprescription of antipsychotics in school-aged children and indicate closer agreement between diagnosis and psychotropic use with age.
Miranda U. Liang, Natchanan Charatcharungkiat, Rebecca Tillman, et al
PCC
Impact of ER Naltrexone on Readmission Rates in Alcohol Use Disorder
Original Research

October 25, 2022

This study evaluated the impact of extended-release intramuscular naltrexone on readmission rates for hospitalized patients with alcohol use disorder.
Jeremy Tigh, Kristin Daniel, Alëna A. Balasanova
JCP
Overlapping Patterns of Suicide Attempts and Non-suicidal Self-Injuries in Adults
Original Research

image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ October 24, 2022

Among adults with self-injury behaviors, switching between episodes with and without suicidal intent is common and is associated with greater risk of suicidal behavior in the future.
Margda Waern, Lotta Strömsten, Stefan Wiktorsson, et al
PCC
Intracerebral Hemorrhage Outcomes and Related Clinical Conditions
Original Research

October 18, 2022

The objective of this study was to identify differences between Saudi and non-Saudi patients regarding demographics, clinical conditions, and associated intracerebral hemorrhage outcomes.
Alia Ali Alokley, Aishah Albakr
JCP
Acceptability of Second-Line Antidepressant Medications
Original Research

October 17, 2022

Second-line antidepressant options were ranked according to acceptability (efficacy and tolerability), using data from the French health system.
Charles Ouazana-Vedrines, Thomas Lesuffleur, Pierre Denis, et al
JCP
Economic Burden of Schizophrenia in the US
Original Research

October 10, 2022

Schizophrenia is associated with significant economic burden, not only for patients but also for families, other caregivers, and the wider society. This study analyzed recent data and literature to...
Aditi Kadakia, Maryaline Catillon, Qi Fan, et al
JCP
Frontothalamic Circuit Abnormalities in Patients With Bipolar Disorder and Suicide Attempts
Original Research

October 5, 2022

To identify potential markers for suicide risk, this fMRI study looked at neural activity in bipolar depression patients with and without suicide attempts and in healthy controls.
Li Zhang, Zhiyong Li, Yu Wu, et al
PCC
Social Media Use Disorder and Emotional Intelligence
Original Research

October 4, 2022

The objective of this article was to investigate the impact of problematic social media use on emotional management, emotional awareness, social emotional awareness, and relationship management.
Reine-Marie Kahwagi, Elsa Sfeir, Sam Barbar, et al
JCP
Sublingual Dexmedetomidine for Agitation in Schizophrenia
Original Research

October 3, 2022

This RCT determined whether a single dose of sublingual dexmedetomidine reduced acute agitation associated with schizophrenia or schizoaffective disorder.
Leslie Citrome, Sheldon H. Preskorn, John Lauriello, et al

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