John H. Krystal, MD

US Department of Veterans Affairs National Center for PTSD, VA Connecticut Healthcare System, West Haven, Connecticut; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut

  • 16Articles
  • 97.3KReads
  • 2001–2026Active
  • 54Collaborators
  • 453Citations

About

John H. Krystal, MD is affiliated with US Department of Veterans Affairs National Center for PTSD, VA Connecticut Healthcare System, West Haven, Connecticut; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut. John H. Krystal has authored or co-authored 16 peer-reviewed articles published across the Journal of Clinical Psychiatry and the Primary Care Companion for CNS Disorders between 2001 and 2026. Their work focuses on Posttraumatic Stress Disorder, Veterans and Military Issues, COVID, Schizophrenia/Schizoaffective Disorders, and Depression (MDD).

Publications

JCP
National Trends in PTSD among US Military Veterans
Original Research

National Trends in PTSD among US Military Veterans

May 25, 2026

Compared with 2019–2020, past-month PTSD prevalence was higher among men, White and racial/ethnic minority veterans, and veterans aged 18–59 years
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JCP
Sublingual Dexmedetomidine for Agitation in Schizophrenia
Original Research

Sublingual Dexmedetomidine for Agitation in Schizophrenia

October 3, 2022

This RCT determined whether a single dose of sublingual dexmedetomidine reduced acute agitation associated with schizophrenia or schizoaffective disorder.
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JCP
Association of Distress Due to Systemic Racism and Racial Disparities With Psychopathology and Suicidal Ideation Among Veterans During COVID-19
Brief Report

Association of Distress Due to Systemic Racism and Racial Disparities With Psychopathology and Suicidal Ideation Among Veterans During COVID-19

August 1, 2022

Data from the National Health and Resilience in Veterans Study shed light on the intersection of systemic racism and the COVID-19 pandemic.
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JCP
PTSD Symptoms and GrimAge, an Epigenetic Marker of Mortality Risk, in Veterans
Brief Report

PTSD Symptoms and GrimAge, an Epigenetic Marker of Mortality Risk, in Veterans

July 6, 2022

This study investigated whether PTSD and other medical and psychiatric conditions were linked to GrimAge, a measure of epigenetic aging, in a large sample of male US veterans.
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JCP
PTSD in US Military Veterans
Original Research

PTSD in US Military Veterans

February 22, 2022

This study sought to determine the likelihood of developing posttraumatic stress disorder (PTSD) after direct versus indirect exposures and examined the effects of direct and indirect PTE exposure and...
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PCC
Brief Report

Resilience in the Face of the COVID-19 Pandemic

November 11, 2021

COVID-19 has presented significant mental health challenges, especially among vulnerable populations. Here, the authors quantify resilience to pandemic-related distress and identify factors associated with greater resilience in a cohort...
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JCP
Letter to the Editor

Functional Polymorphism in Neuropeptides and Resilience to Traumatic Stress

October 25, 2017

Neuropeptide Y plays a key role in the regulation of fear, stress, and memory. To probe the mechanisms of, and possible interventions for, traumatic stress, the small study reported...
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JCP
Original Research

Prevalence of PTSD According to the DSM-5

November 23, 2016

Some have argued that changes to the diagnostic criteria for PTSD in the DSM-5 would increase rates of comorbidity between PTSD and other psychiatric disorders. Find out whether that...
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JCP
Original Research

Sleep Disturbance in Chronic Military-Related PTSD: Clinical Impact and Response to Adjunctive Risperidone in the Veterans Affairs Cooperative Study #504

April 27, 2016

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JCP
Article

Late-Life PTSD Exacerbation

March 23, 2016

Do you see patients who are older military veterans? Did you know that some experience exacerbated posttraumatic stress disorder (PTSD) symptoms, possibly decades after their trauma? Read this journal...
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JCP
Original Research

Dimensional Structure of DSM-5 Posttraumatic Stress Disorder Symptoms: Results From the National Health and Resilience in Veterans Study

November 11, 2014

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JCP
Original Research

Cost and Cost-Effectiveness in a Randomized Trial of Long-Acting Risperidone for Schizophrenia

May 15, 2012

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Physicians Postgraduate Press, Inc. (PPP) makes no warranties about the accuracy or completeness of any information published in The Journal of Clinical Psychiatry or other PPP materials, and disclaims liability for any use or non-use of that information. Clinicians should not rely solely on these materials and should exercise their own professional judgment when making patient care decisions on an individualized basis.

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