Masaru Mimura, MD, PhD
Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan
Review Article
Central and Peripheral Pharmacokinetics of Antipsychotics
July 28, 2020
Pharmacokinetics of antipsychotics are generally slower centrally than peripherally. This review examined the possible dissociation between central D2 receptor occupancy with antipsychotics and their peripheral blood concentrations.
Original Research
Early Improvements Predict Treatment Response in Alzheimer's
February 11, 2020
Can overall response to antipsychotics be predicted by early improvements in individual symptoms among Alzheimer's disease patients? The current report analyzes the CATIE-AD phase 1 dataset in an attempt...
Article
Increasing Versus Maintaining the Dose of Olanzapine or Risperidone in Schizophrenia Patients Who Did Not Respond to a Modest Dosage: A Double-Blind Randomized Controlled Trial
October 26, 2016
When your patients with schizophrenia insufficiently respond to antipsychotic treatment, do you increase the dose? Do you check their plasma drug concentration? Read this CME article to find out...