Sidney H. Kennedy, MD
Department of Psychiatry, University of Toronto, Toronto, Canada
Original Research
Machine Learning Prediction of Quality of Life Improvement During Antidepressant Treatment of Patients With Major Depressive Disorder: A STAR*D and CAN-BIND-1 Report
November 15, 2023
Quality of life is an important patient-centric outcome. Using machine learning methods, this study found that quality of life improvement with antidepressant treatment can be predicted using early depression...
Original Research
Worsening of Suicidal Ideation During AD Treatment
May 7, 2019
Antidepressants are effective in preventing suicide, but some antidepressant-treated patients experience increased suicidal ideation. Read this article to learn if clinical features and biomarkers can predict worsened suicidal ideation...
Original Research
CAN-BIND-1 Outcomes and Early Response Prediction in MDD
February 5, 2019
Antidepressant medications are often prescribed with little certainty about their potential effectiveness in individual patients. Can early symptom reduction help predict later symptomatic and functional outcomes of antidepressant treatment?...
Article
A Review of Antidepressant Therapy in Primary Care: Current Practices and Future Directions
April 11, 2013
The authors of this study provide general practitioners with a comparison of major depressive disorder treatments received in primary care and psychiatric clinic settings, a focus on treatment outcomes...
Article
Attention-Deficit/Hyperactivity Disorder in Adults With Bipolar Disorder or Major Depressive Disorder: Results From the International Mood Disorders Collaborative Project
May 27, 2010
What are the clinical implications of lifetime attention-deficit/hyperactivity disorder (ADHD) in adults with a mood disorder? The primary aim of this study was to determine the prevalence and clinical...
