Psychotic Disorders

Psychotic disorders, including schizophrenia, are characterized by delusions, hallucinations, and disorganized thinking. The Journal of Clinical Psychiatry offers comprehensive insights into these disorders, from their neurobiological underpinnings to evidence-based therapeutic strategies. Our expert editors ensure content is both actionable and holistic, aiding psychiatrists in offering comprehensive care to individuals with psychotic disorders.

Recently published article about Psychotic Disorders

JCP
Economic Impact of Cognitive Impairment and Negative Symptoms in Schizophrenia
Review Article

August 21, 2024

Patients with schizophrenia and cognitive impairment had a 100% increase in relapse-related hospitalizations and ER visits versus patients with no (or only mild) cognitive impairment.
Christoph U. Correll, Pin Xiang, Kaushik Sarikonda, et al
JCP
Aripiprazole Lauroxil Initiation Regimens
Original Research

August 12, 2024

In separate studies of the two initiation methods, the numbers of people who had side effects were similar, and most side effects were mild.
Roger W. Sommi, Stephen R. Saklad, Peter J. Weiden, et al
PCC
Steroid-Induced Musical Hallucinosis
Case Report

August 8, 2024

A 59-year-old man with no prior psychiatric history developed musical hallucinations following the administration of methylprednisolone.
Jon Sole, Shixie Jiang, Matthew Gunther
PCC
Clozapine-Related Cecal Volvulus
Case Report

July 11, 2024

This case of clozapine-related cecal volvulus illustrates the need for a high index of suspicion for potentially life-threatening surgical emergencies in clozapine-treated patients.
Sharlo L. Bayless, Nathaniel V. Walker, Maxwell M. Scott, et al
Weekly Mind Reader: Why Its Time to Rethink Tobacco Use Disorder
news

June 14, 2024

New research suggests that it might be time to reconsider what we think we know about tobacco use disorder (TUD) in the United States.
PCC
Psychosis With Use of an Herbal Chinese Slimming Product
Case Report

June 11, 2024

A woman with no underlying mood disorder experienced psychotic symptoms after taking an herbal appetite suppressant.
Meghana Rao, Madeline Riney, Kaushal Shah, et al

Recent JCP Articles on Psychotic Disorders

JCP
Valproate and Weight Gain: A New Look at an Old Problem
Commentary

March 27, 2024

Dr Goldberg comments on a recent cohort study demonstrating a dose relationship with weight gain liability for valproate.
Joseph F. Goldberg
JCP
Associations of Valproate Doses With Weight Gain in Psychiatric Patients
Original Research

March 27, 2024

Valproate dose increase of 500 mg was associated with a weight change of +0.52% per month over a year. No associations were found between valproate dose and blood glucose,...
Claire Grosu, William Hatoum, Marianna Piras, et al
JCP
Does the Onset of Efficacy for Agitation Vary Depending on the Administration Route of Antipsychotics?
Letter to the Editor

March 20, 2024

As choice of administration route is crucial during psychiatric emergencies, the authors stress the need for RCTs comparing onset of efficacy for agitation across different administration routes of the...
Xintong Mu, Hiroyoshi Takeuchi

Recent PCC Articles on Psychotic Disorders

PCC
Psychotic Symptoms Following Ayahuasca Use
Case Report

April 11, 2024

A 43-year-old woman with no psychiatric history developed schizophreniform psychotic symptoms after taking ayahuasca, which resolved after 1 week of risperidone treatment.
Alfonso Martínez Torres, Eduardo Prades Marín, Patricia Sánchez Díez, et al
PCC
Risperidone Exposure During Pregnancy and Breastfeeding
Case Report

February 1, 2024

The authors present an unusual case of a woman with continuous use of risperidone and trihexyphenidyl for many years, who gave birth to 5 healthy children during that time.
Dattatraya Mendhekar, Chittaranjan Andrade
PCC
Homicidal Ideation After Watching Jeffrey Dahmer Netflix Drama
Case Report

January 23, 2024

The authors discuss 2 cases of adolescents with no prior psychiatric history who presented with suicidal and homicidal ideation after watching Dahmer—Monster: The Jeffrey Dahmer Story.
Tyler J. Thompson, Brandon Chen, Tanner Mabry, et al

The latest news on Psychotic Disorders

Featured Psychotic Disorders Research

JCP
Effects of Prenatal Exposure to Second-Generation Antipsychotics on Development and Behavior in Preschool-Aged Children
Original Research

March 13, 2024

Outcomes of children exposed in utero to second-generation antipsychotics (SGAs) were compared to those of children unexposed to SGAs in a cohort of mothers with a history of psychiatric...
Carol Swetlik, Lee S. Cohen, Lauren A. Kobylski, et al
JCP
Pharmacist-Led Telehealth for People With Psychosis or Bipolar Disorder
Original Research

January 29, 2024

A telehealth collaborative care program with psychiatric clinical pharmacists had strong patient participation and was associated with greater medication adherence and guideline-concordant preventive care.
Esti Iturralde, Lisa Fazzolari, Natalie E. Slama, et al
PCC
Catatonia and Psychosis With Hyperthyroidism
Case Report

November 23, 2023

Catatonia is a rare manifestation of hyperthyroidism. This report describes a case of catatonia and psychosis resulting from hyperthyroidism in a woman with no previous psychiatric history.
Hadley W. Ressler, Kaushal Shah, Taylor Quattlebaum, et al
JCP
Enhancing Postpartum Psychosis Care
Commentary

May 29, 2024

The authors discuss the need for qualitative research to fill gaps in the current understanding of postpartum psychosis, as well as the barriers that make conducting this research a...
Lauren A. Kobylski, Huynh-Nhu Le, Marlene P. Freeman, et al
JCP
Psychosis, Inflammatory Biomarkers, and Subtypes of Childhood Trauma
Commentary

May 22, 2024

Dr Nasrallah discusses a recent study by Cuñat et al of the relationship between childhood trauma and inflammation, and why this work is unique and important.
Henry A. Nasrallah
Weekly Mind Reader: Clozapine Research, Esmethadone Efficacy, and Our First Reader Mailbag
news

May 16, 2024

This week we report on a bevy of clozapine research, a promising Esmethadone case study, and let our readers take it from there.
JCP
Antipsychotic Medication Continuation vs Taper and Discontinuation
Clinical and Practical Psychopharmacology

May 15, 2024

Dr Andrade discusses two studies that examined the outcomes of gradual, individualized antipsychotic dose reduction and discontinuation in patients with psychosis.
Chittaranjan Andrade
Study Reveals Unique Trait Among Female Psychopaths
news

May 14, 2024

Researchers found that women with high psychopathy scores exhibit minimal head movement, a nonverbal cue also seen in male psychopaths.
JCP
Clozapine Use and Specific Indications
Original Research

April 29, 2024

Clozapine initiation is uncommon in people with psychotic disorders who have experienced events suggesting clozapine is indicated, with even lower rates in Black and Hispanic patients.
Gregory E. Simon, Rebecca C. Rossom, Esti Iturralde, et al

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