As part of Psychiatrist.com News’ Editorial Focus, this collection highlights the latest developments in schizophrenia treatment, emphasizing new therapies that go beyond traditional dopaminergic approaches. Clinicians will gain insights into managing negative symptoms, cognitive impairments, and the functional, emotional, and economic burdens of schizophrenia. Articles cover topics such as cholinergic neurotransmission, novel therapeutic mechanisms, and strategies aimed at improving patient outcomes, offering practical knowledge to support clinical practice.