Original Research May 1, 2023

Impact of the Abbreviated Suicide Crisis Syndrome Checklist on Clinical Decision Making in the Emergency Department

Ethan Karsen, MD; Lisa J. Cohen, PhD; Betsy White, LCSW; Gabriele P. De Luca, MD; Inna Goncearenco; Igor I. Galynker, MD; Frederick E. Miller, MD, PhD

J Clin Psychiatry 2023;84(3):22m14655

ABSTRACT

Objective: The suicide crisis syndrome (SCS), an acute negative affect state predictive of near-term suicidal behavior, is currently under review for inclusion as a suicide-specific diagnosis in the Diagnostic and Statistical Manual of Mental Disorders (DSM). While the predictive validity of the SCS for near-term suicidal behavior is well documented, its real-world clinical utility has yet to be evaluated. As such, this study evaluated how implementation of a novel assessment tool, the Abbreviated SCS Checklist (A-SCS-C), into the electronic medical records (EMRs) influenced disposition decisions in the emergency departments (EDs) of a large urban health system.

Methods: Logistic regression analyses evaluated the impact of SCS diagnosis on 212 admission/discharge decisions after accounting for chief complaints of suicidal ideation (SI), suicidal behavior (SB), and psychosis/agitation.

Results: The A-SCS-C was concordant with 86.9% of all non-psychotic disposition decisions. In multivariable analysis, the A-SCS-C had an adjusted odds ratio (AOR) of 65.9 (95% confidence interval: 18.79–231.07) for inpatient admission, whereas neither suicidal ideation nor behavior was a significant predictor. The effect size remained very high in 3 sensitivity analyses, the first using information from a different section of the EMR, the second in patients younger than 18 years, and the third in males and females separately (AORs > 30).

Conclusions: SCS diagnosis, when implemented in ED EMRs alongside SI and SB, was strongly predictive of clinician decision making with regard to admission/discharge, particularly in non-psychotic patients, while SI and SB were noncontributory. Overall, our results show that the SCS, as a diagnostic entity, demonstrates robust clinical utility and may reduce the limitations of relying on self-reported SI as a primary basis of suicide risk assessment.

Continue Reading...

Did you know members enjoy unlimited free PDF downloads as part of their subscription? Subscribe today for instant access to this article and our entire library in your preferred format. Alternatively, you can purchase the PDF of this article individually.

Subscribe Now

Already a member? Login

Purchase PDF for $40

Members enjoy free PDF downloads on all articles. Join today

  1. Centers for Disease Control and Prevention. WISQARS: Web-Based Inquiry Statistics Query and Reporting System. Updated December 2, 2021. Accessed February 2, 2022. https://www.cdc.gov/injury/wisqars/index.html
  2. Hedegaard H, Curtin SC, Warner M. Suicide mortality in the United States, 1999–2019. NCHS Data Brief. 2021;(398):1–8. PubMed CrossRef
  3. World Health Organization. Suicide data. Accessed December 2, 2022. https://www.who.int/teams/mental-health-and-substance-use/data-research/suicide-data
  4. World Health Organization. World health statistics 2022: monitoring health for the SDGs, sustainable development goals. Accessed December 2, 2022. https://www.who.int/data/gho/publications/world-health-statistics
  5. Tucker RP, Michaels MS, Rogers ML, et al. Construct validity of a proposed new diagnostic entity: Acute Suicidal Affective Disturbance (ASAD). J Affect Disord. 2016;189:365–378. PubMed CrossRef
  6. Rogers ML, Chu C, Joiner T. The necessity, validity, and clinical utility of a new diagnostic entity: acute suicidal affective disturbance. J Clin Psychol. 2019;75(6):999–1010. PubMed CrossRef
  7. Voros V, Tenyi T, Nagy A, et al. Crisis concept re-loaded? the recently described suicide-specific syndromes may help to better understand suicidal behavior and assess imminent suicide risk more effectively. Front Psychiatry. 2021;12:598923. PubMed CrossRef
  8. Galynker I, Yaseen ZS, Cohen A, et al. Prediction of suicidal behavior in high risk psychiatric patients using an assessment of acute suicidal state: the Suicide Crisis Inventory. Depress Anxiety. 2017;34(2):147–158. PubMed CrossRef
  9. Yaseen ZS, Kopeykina I, Gutkovich Z, et al. Predictive validity of the Suicide Trigger Scale (STS-3) for post-discharge suicide attempt in high-risk psychiatric inpatients. PLoS One. 2014;9(1):e86768. PubMed CrossRef
  10. Schuck A, Calati R, Barzilay S, et al. Suicide crisis syndrome: a review of supporting evidence for a new suicide-specific diagnosis. Behav Sci Law. 2019;37(3):223–239. PubMed CrossRef
  11. Calati R, Nemeroff CB, Lopez-Castroman J, et al. Candidate biomarkers of suicide crisis syndrome: what to test next? a concept paper. Int J Neuropsychopharmacol. 2020;23(3):192–205. PubMed CrossRef
  12. Rogers M, Galynker I, Yaseen Z, et al. An overview and comparison of two proposed suicide-specific diagnoses: acute suicidal affective disturbance and suicide crisis syndrome. Psychiatr Ann. 2017;47(8):416–420. CrossRef
  13. Høyen KS, Solem S, Cohen LJ, et al. Non-disclosure of suicidal ideation in psychiatric inpatients: rates and correlates. Death Stud. 2022;46(8):1823–1831. PubMed CrossRef
  14. Rumschik SM, Appel JM. Malingering in the psychiatric emergency department: prevalence, predictors, and outcomes. Psychiatr Serv. 2019;70(2):115–122. PubMed CrossRef
  15. Deisenhammer EA, Ing CM, Strauss R, et al. The duration of the suicidal process: how much time is left for intervention between consideration and accomplishment of a suicide attempt? J Clin Psychiatry. 2009;70(1):19–24. PubMed CrossRef
  16. Berman AL. Risk factors proximate to suicide and suicide risk assessment in the context of denied suicide ideation. Suicide Life Threat Behav. 2018;48(3):340–352. PubMed CrossRef
  17. Busch KA, Fawcett J, Jacobs DG. Clinical correlates of inpatient suicide. J Clin Psychiatry. 2003;64(1):14–19. PubMed CrossRef
  18. Stone DM, Simon TR, Fowler KA, et al. Vital signs: trends in state suicide rates—United States, 1999–2016 and circumstances contributing to suicide—27 states. MMWR Morb Mortal Wkly Rep. 2018;67(22):617-624. CrossRef
  19. Katz C, Yaseen ZS, Mojtabai R, et al. Panic as an independent risk factor for suicide attempt in depressive illness: findings from the National Epidemiological Survey on Alcohol and Related Conditions (NESARC). J Clin Psychiatry. 2011;72(12):1628–1635. PubMed CrossRef
  20. Yaseen ZS, Chartrand H, Mojtabai R, et al. Fear of dying in panic attacks predicts suicide attempt in comorbid depressive illness: prospective evidence from the National Epidemiological Survey on Alcohol and Related Conditions. Depress Anxiety. 2013;30(10):930–939. PubMed CrossRef
  21. Rappaport LM, Moskowitz DS, Galynker I, et al. Panic symptom clusters differentially predict suicide ideation and attempt. Compr Psychiatry. 2014;55(4):762–769. PubMed CrossRef
  22. Li S, Galynker II, Briggs J, et al. Attachment style and suicide behaviors in high risk psychiatric inpatients following hospital discharge: the mediating role of entrapment. Psychiatry Res. 2017;257:309–314. PubMed CrossRef
  23. Hawes M, Galynker I, Barzilay S, et al. Anhedonia and suicidal thoughts and behaviors in psychiatric outpatients: the role of acuity. Depress Anxiety. 2018;35(12):1218–1227. PubMed CrossRef
  24. Barzilay S, Assounga K, Veras J, et al. Assessment of near-term risk for suicide attempts using the Suicide Crisis Inventory. J Affect Disord. 2020;276:183–190. PubMed CrossRef
  25. Bloch-Elkouby S, Gorman B, Lloveras L, et al. How do distal and proximal risk factors combine to predict suicidal ideation and behaviors? a prospective study of the narrative crisis model of suicide. J Affect Disord. 2020;277:914–926. PubMed CrossRef
  26. Bloch-Elkouby S, Barzilay S, Gorman BS, et al. The revised Suicide Crisis Inventory (SCI-2): validation and assessment of prospective suicidal outcomes at one month follow-up. J Affect Disord. 2021;295:1280–1291. PubMed CrossRef
  27. Bloch-Elkouby S, Gorman B, Schuck A, et al. The suicide crisis syndrome: a network analysis. J Couns Psychol. 2020;67(5):595–607. PubMed CrossRef
  28. Calati R, Cohen LJ, Schuck A, et al. The Modular Assessment of Risk for Imminent Suicide (MARIS): a validation study of a novel tool for suicide risk assessment. J Affect Disord. 2020;263:121–128. PubMed CrossRef
  29. Rogers ML, Bafna A, Galynker I. Comparative clinical utility of screening for suicide crisis syndrome versus suicidal ideation in relation to suicidal ideation and attempts at one-month follow-up. Suicide Life Threat Behav. 2022;52(5):866–875. PubMed CrossRef
  30. Yaseen ZS, Hawes M, Barzilay S, et al. Predictive validity of proposed diagnostic criteria for the suicide crisis syndrome: an acute presuicidal state. Suicide Life Threat Behav. 2019;49(4):1124–1135. PubMed CrossRef
  31. Ying G, Cohen LJ, Lloveras L, et al. Multi-informant prediction of near-term suicidal behavior independent of suicidal ideation. Psychiatry Res. 2020;291:113169. PubMed CrossRef
  32. Fredriksen KJ, Bartz-Johannessen C, Schoeyen HK, et al. Imminent and short-term risk of death by suicide in 7,000 acutely admitted psychiatric inpatients. J Clin Psychiatry. 2022;84(1):22m14460. PubMed CrossRef
  33. American Psychological Association. Criteria for evaluating treatment guidelines. Am Psychol. 2002;57(12):1052–1059. PubMed CrossRef
  34. First MB, Pincus HA, Levine JB, et al. Clinical utility as a criterion for revising psychiatric diagnoses. Am J Psychiatry. 2004;161(6):946–954. PubMed CrossRef
  35. First MB. Clinical utility in the revision of the Diagnostic and Statistical Manual of Mental Disorders (DSM). Prof Psychol Res Pr. 2010;41(6):465–473. CrossRef
  36. Reed GM. Toward ICD‐11: improving the clinical utility of WHO’s international classification of mental disorders. Prof Psychol Res Pr. 2010;41(6):457–464. CrossRef
  37. Goldman-Mellor S, Olfson M, Lidon-Moyano C, et al. Association of suicide and other mortality with emergency department presentation. JAMA Netw Open. 2019;2(12):e1917571. PubMed CrossRef
  38. McPherson S, Hale R, Richardson P, et al. Stress and coping in accident and emergency senior house officers. Emerg Med J. 2003;20(3):230–231. PubMed CrossRef
  39. Shanafelt TD, Boone S, Tan L, et al. Burnout and satisfaction with work-life balance among US physicians relative to the general US population. Arch Intern Med. 2012;172(18):1377–1385. PubMed CrossRef
  40. Chisholm CD, Weaver CS, Whenmouth L, et al. A task analysis of emergency physician activities in academic and community settings. Ann Emerg Med. 2011;58(2):117–122. PubMed CrossRef
  41. Galynker I, Yaseen Z, Briggs J. Assessing risk for imminent suicide. Psychiatr Ann. 2014;44(9):431–436. CrossRef
  42. Posner K, Brent D, Lucas C, et al. Columbia-Suicide Severity Rating Scale: Screen Version—Recent. New York State Psychiatric Institute. Updated January 14, 2009. Accessed March 5, 2020. https://cssrs.columbia.edu/wp-content/uploads/C-SSRS-Screening_AU5.1_eng-USori.pdf
  43. Goldberg JF, Ernst CL, Bird S. Predicting hospitalization versus discharge of suicidal patients presenting to a psychiatric emergency service. Psychiatr Serv. 2007;58(4):561–565. PubMed CrossRef
  44. Walker S, Mackay E, Barnett P, et al. Clinical and social factors associated with increased risk for involuntary psychiatric hospitalisation: a systematic review, meta-analysis, and narrative synthesis. Lancet Psychiatry. 2019;6(12):1039–1053. PubMed CrossRef
  45. Seifert J, Ihlefeld C, Zindler T, et al. Sociodemographic, circumstantial, and psychopathological predictors of involuntary admission of patients with acute psychosis. Psychiatry International. 2021;2(3):310–324. CrossRef
  46. Hong V, Pirnie L, Shobassy A. Antisocial and borderline personality disorders in the emergency department: conceptualizing and managing “malingered” or “exaggerated” symptoms. Curr Behav Neurosci Rep. 2019;6(4):127–132. CrossRef
  47. Galynker I, Ieronimo C, Perez-Acquino A, et al. Panic attacks with psychotic features. J Clin Psychiatry. 1996;57(9):402–406. PubMed
  48. Oquendo MA, Baca-Garcia E. Suicidal behavior disorder as a diagnostic entity in the DSM-5 classification system: advantages outweigh limitations. World Psychiatry. 2014;13(2):128–130. PubMed CrossRef
  49. Oquendo MA, Baca-García E, Mann JJ, et al. Issues for DSM-V: suicidal behavior as a separate diagnosis on a separate axis. Am J Psychiatry. 2008;165(11):1383–1384. PubMed CrossRef
  50. Sisti D, Mann JJ, Oquendo MA. Toward a distinct mental disorder-suicidal behavior. JAMA Psychiatry. 2020;77(7):661–662. PubMed CrossRef
  51. Chu C, Klein KM, Buchman-Schmitt JM, et al. Routinized assessment of suicide risk in clinical practice: an empirically informed update. J Clin Psychol. 2015;71(12):1186–1200. PubMed CrossRef
  52. Ribeiro J, Bodell L, Hames J, et al. An empirically based approach to the assessment and management of suicidal behavior. J Psychother Integration. 2013;23(3):207–221. CrossRef
  53. Silverman MM, Berman AL. Feeling ill at ease with a new disease. Crisis. 2020;41(4):241–247. PubMed CrossRef
  54. Silverman MM, Berman AL. Suicide risk assessment and risk formulation part I: a focus on suicide ideation in assessing suicide risk. Suicide Life Threat Behav. 2014;44(4):420–431. PubMed CrossRef
  55. Hawton K, Lascelles K, Pitman A, et al. Assessment of suicide risk in mental health practice: shifting from prediction to therapeutic assessment, formulation, and risk management. Lancet Psychiatry. 2022;9(11):922–928. PubMed CrossRef
  56. Cohen LJ, Imbastaro B, Peterkin D, et al. Suicide crisis syndrome: the necessity, conceptual clarity, and clinical utility of a new suicide-specific diagnosis. Crisis. Forthcoming.
  57. Ambrosetti J, Macheret L, Folliet A, et al. Psychiatric emergency admissions during and after COVID-19 lockdown: short-term impact and long-term implications on mental health. BMC Psychiatry. 2021;21(1):465. PubMed CrossRef
  58. Mitchell L, Fuehrlein B. Patient volume and dispositions in a VA psychiatric emergency room during COVID-19. Community Ment Health J. 2021;57(7):1237–1239. PubMed CrossRef
  59. Michaud L, Berva S, Ostertag L, et al. When to discharge and when to voluntary or compulsory hospitalize? Factors associated with treatment decision after self-harm. Psychiatry Res. 2022;317:114810. PubMed CrossRef
  60. Simon GE, Johnson E, Lawrence JM, et al. Predicting suicide attempts and suicide deaths following outpatient visits using electronic health records. Am J Psychiatry. 2018;175(10):951–960. PubMed CrossRef