Perspective November 26, 2013

Addressing Concerns About the Inclusion of Premenstrual Dysphoric Disorder in DSM-5

S. Ann Hartlage, PhD; Cynthia A. Breaux, PhD; Kimberly A. Yonkers, MD

J Clin Psychiatry 2014;75(1):70-76

Article Abstract

Objective: Inclusion of premenstrual dysphoric disorder (PMDD) into the main text of the DSM has been a point of controversy for many years. The purpose of this article is to address the main concerns raised by opponents to its inclusion. Concerns are presented and countered in turn.

Literature Search: To identify the most prevalent arguments against inclusion of PMDD, we searched MEDLINE (1966-2012), PsycINFO (1930-2012), the Internet, and reference lists of identified articles during September 1-17, 2012, using the keywords PMDD, premenstrual syndrome (PMS), DSM, DSM-5, concerns, controversy, women, political power, workforce, courts, and history. The search was restricted to English-language publications. A total of 55 articles were identified and included. The most pressing arguments against inclusion were grouped by similarity and addressed if they were reported 5 or more times. Our review of the sources yielded 38 concerns regarding PMDD; 6 concerns were reported at least 5 times and are addressed in this article.

Discussion: Evidence culled from historical and legal trends does not support the alleged societal use of PMS to harm women (eg, keeping women out of the workforce or using PMS against women in child custody disputes). Further, current epidemiologic research has answered all of the methodology criticisms of opponents. Studies have confirmed the existence of PMDD worldwide. The involvement of pharmaceutical companies in research has been questioned. However, irrespective of the level of association with industry, current research on PMDD has consistent results: PMDD exists in a minority of women.

Conclusions: Historically, the pain and suffering of women have been dismissed, minimized, and negated. Similarly, women with PMDD have often had their experience invalidated. With the preponderance of evidence in its favor, PMDD has been placed in the main text of the DSM-5, opening the door for affected women to receive the attention full diagnostic status provides.

J Clin Psychiatry

Submitted: January 13, 2013; accepted September 20, 2013.

Online ahead of print: November 26, 2013 (doi:10.4088/JCP.13cs08368).

Corresponding author: S. Ann Hartlage, PhD, Department of Psychiatry, Rush University Medical Center, 2150 W Harrison St, Chicago, IL 60612 ([email protected]).

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