Advances in Diagnosis of Alzheimer Disease and Emerging Treatment Targets

Until recently, the diagnosis of Alzheimer disease (AD) could not be truly made until an autopsy was done. Patients’ diagnosis relied on clinicians’ skills to recognize signs and symptoms of AD, and the diagnosis was often incorrect. The rate of misdiagnosis was higher in earlier disease stages when symptoms are milder. Researchers have made great strides over the past 2 decades in identifying diagnostic biomarkers and treatment targets. Can AD now be diagnosed before patients show symptoms? What do potential treatments look like? This CME presentation highlights exciting developments.