Anetholtrithion Stabilizes Body Weight Fluctuation Caused by Excessive Water Drinking in a Patient With Schizophrenia: A Case Report

Letter to the Editor

Sir: Treatment approaches for schizophrenic patients manifesting severe polydipsia include changing antipsychotic drugs, changing drug dosage, and stopping anticholinergic drugs used to treat movement disorders. Antipsychotic drugs and smoking are thought to contribute to polydipsia in schizophrenia, but the exact cause remains unknown. Some schizophrenic patients are placed in isolation to restrict access to water and, thus, prevent dilutional hyponatremia and subsequent generalized seizures. We need better treatments for severe polydipsia in schizophrenia.