Editorial
Review Article
Review Article
Cognitive Effects of Electroconvulsive Therapy in Schizophrenia: A Systematic Review
June 5, 2024
ECT was not associated with any significant cognitive deficits in people with treatment-resistant schizophrenia across global cognition, attention, language, visuospatial function, and executive function domains. The majority of studies...
Original Research
Original Research
Comorbidity and Quality of Life in DSM-5 Social Anxiety Disorder Among a Nationally Representative Sample
May 27, 2024
Depression, anxiety disorders, PTSD, and borderline personality disorder were associated with social anxiety disorder (SAD). Presence of these disorders was also associated with poorer mental health in those with...
Original Research
Risk for Suicide and Homicide Peaks at Night: Findings From the National Violent Death Reporting System, 35 States, 2003–2017
May 29, 2024
Risk for suicide and homicide is greater at night than expected based on the number of people awake at that time. Nighttime risk was greater among young adults and...
Original Research
A Randomized, Double-Blind, Placebo-Controlled Pilot Trial of the Acute Antisuicidal and Antidepressant Effects of Intranasal (R,S)-Ketamine in Severe Unipolar and Bipolar Depression With and Without Comorbid Alcohol Use Disorder
April 24, 2024
Intranasal ketamine induced rapid antidepressant effects versus placebo but did not significantly change suicidal ideation scores in patients with alcohol use disorder and suicidal ideation with past attempt.
Original Research
Clozapine Use Among People With Psychotic Disorders Who Experience Specific Indications for Clozapine
April 29, 2024
Clozapine initiation is uncommon in people with psychotic disorders who have experienced events suggesting clozapine is indicated, with even lower rates in Black and Hispanic patients.
Original Research
Associations of Valproate Doses With Weight Gain in Adult Psychiatric Patients: A 1-Year Prospective Cohort Study
March 27, 2024
Valproate dose increase of 500 mg was associated with a weight change of +0.52% per month over a year. No associations were found between valproate dose and blood glucose,...
Original Research
Severity of Antipsychotic-Induced Cervical Dystonia Assessed by the Algorithm-Based Rating System
April 15, 2024
Rater consensus data were compared with deviation angle data using AI-based deviation angle measurement technology. With the range of tilt angles found in the study, the authors propose a...
Original Research
Psychological Pain as a Risk Factor for Suicidal Ideation: An Ecological Momentary Assessment Study on Inpatients With Depression With and Without Comorbid Borderline Personality Disorder
April 8, 2024
In inpatients with depression, psychological pain is a risk factor for suicidal ideation. Those with borderline personality disorder may experience more prominent and temporally unstable psychological pain, likely underlying...
Original Research
Beneficial Effects of Concomitant Long-Acting Injectable Antipsychotics on Time to Rehospitalization in Patients With Treatment-Resistant Schizophrenia Receiving Clozapine: A Retrospective Cohort Study
May 1, 2024
Clozapine plus LAI antipsychotics was associated with lower risk of rehospitalization compared to both clozapine plus oral antipsychotics and clozapine monotherapy.
Original Research
A Fully Remote Randomized Trial of Transcranial Alternating Current Stimulation for the Acute Treatment of Major Depressive Disorder
April 22, 2024
Rapid improvement in depression was associated with tACS, particularly for women. Patients can use tACS treatment on their own at home, and it is associated with minimal adverse events.
Original Research
Effects of a Multicomponent Intervention With Cognitive Training and Lifestyle Guidance for Older Adults at Risk of Dementia: A Randomized Controlled Trial
May 13, 2024
This randomized controlled trial of cognitive training plus lifestyle guidance demonstrated improved cognitive function in community-dwelling older adults at risk of dementia.
Original Research
A Combined Index Using the Mini-Mental State Examination and Lawton Index to Discriminate Between Clinical Dementia Rating Scores of 0.5 and 1: A Development and Validation Study
May 20, 2024
A combined index from the MMSE and Lawton Index performed well in discriminating between Clinical Dementia Rating scores of 0.5 and 1.
Original Research
Pharmacogenomic Characterization of Childbearing-Aged Individuals With Mood Disorders in a Tertiary Care Perinatal Mental Health Clinic
June 10, 2024
In patients of childbearing age who have had atypical responses or side effects to antidepressants, pharmacogenomic testing may be considered to guide dose or choice of agent. Dose adjustments...
Original Research
Longitudinal Trajectories of Depressive Symptoms and Their Associations With Risks of Underweight and Obesity in Women: A Population-Based Longitudinal Study in Korea
June 3, 2024
Women with persistently high levels of depressive symptoms had an escalating risk of both underweight and obesity over the 6 years of follow-up.
Original Research
Relationship Between Exposure to Emotional Neglect and the Inflammatory Biomarkers Neutrophil-to-Lymphocyte, Monocyte-to-Lymphocyte, and Platelet-to-Lymphocyte Ratios in Patients With First-Episode Psychosis
May 22, 2024
The authors examined the link between the immune system and childhood traumatic events in patients with first-episode psychosis.
Original Research
Daily and Cumulative Sleep Duration as Predictors of Suicidal Desire and Intent: An Ecological Momentary Assessment Study
June 3, 2024
Both fewer hours of typical sleep and decreases in sleep in an individual night compared to one’s norm may be acute indicators of increased suicide risk.
Original Research
What’s Gender Got to Do With It: Accounting for Differences in Incident Guideline Discordant Prescribing for PTSD Among Women and Men Veterans
June 5, 2024
Women Veterans with PTSD were 67% more likely to initiate a guideline discordant medication. More than half of this effect was explained by bipolar disorder, age, and prior psychiatric...
Commentary
Commentary
Enhancing Postpartum Psychosis Care With Qualitative Research: Current Findings and Future Directions
May 29, 2024
The authors discuss the need for qualitative research to fill gaps in the current understanding of postpartum psychosis, as well as the barriers that make conducting this research a...
Clinical and Practical Psychopharmacology
Clinical and Practical Psychopharmacology
Antipsychotic Medication Continuation vs Taper and Discontinuation in Patients With Schizophrenia and Other Nonaffective Psychotic Disorders
May 15, 2024
Dr Andrade discusses two studies that examined the outcomes of gradual, individualized antipsychotic dose reduction and discontinuation in patients with psychosis.
Clinical and Practical Psychopharmacology
Epilepsy, Antiepileptic Drugs, and Adverse Pregnancy Outcomes, 1: Examination and Interpretation of Recent Research
June 5, 2024
This article provides women who have epilepsy and who use antiepileptic drugs during pregnancy with information about the many risks to which they and their fetus/neonate are exposed at...
ASCP Corner
Case Report
Case Report
Serotonin Syndrome and Dextromethorphan Toxicity Caused by Drug-Drug Interaction Between Fluoxetine and Bupropion-Dextromethorphan: A Case Report
April 3, 2024
Addition of bupropion-dextromethorphan (BUP/DXM) to existing fluoxetine treatment resulted in serotonin syndrome within 3 days, with symptoms prompting presentation to the ED 5 days after discontinuation of BUP/DXM.
Letter to the Editor
Letter to the Editor
Does the Onset of Efficacy for Agitation Vary Depending on the Administration Route of Antipsychotics?
March 20, 2024
As choice of administration route is crucial during psychiatric emergencies, the authors stress the need for RCTs comparing onset of efficacy for agitation across different administration routes of the...
Letter to the Editor
Why Ask Patients to Cut Into Quarters 10-mg THC Gummies Obtained From a Cannabis Dispensary When 2.5-mg THC (Dronabinol) Is Available by Prescription?
June 5, 2024
The authors discuss a study by Sawicki et al of dementia patients for whom 2.5 mg of THC was recommended for neuropsychiatric symptoms.
Letter to the Editor
Prevalence of Psychiatric Disorders in Women With Obstetric Complications: Results From the National Epidemiologic Survey on Alcohol and Related Conditions-III
May 27, 2024
Obstetric complications are associated with a higher prevalence of mood and anxiety disorders during the perinatal period.
