Aripiprazole-Induced Psychosis: A Case Report of Reexposure by Stepwise Up-Titration

Because this piece does not have an abstract, we have provided for your benefit the first 3 sentences of the full text.

Sir: Aripiprazole is a new atypical antipsychotic with a partial agonist activity at D₂ and 5-HT_1A receptors and with potent 5-HT_2A receptor antagonism. Dose titration is considered necessary by some authors,¹ but not by others.^2,3 Recently, multiple cases of worsening of psychotic symptoms after add-on treatment with aripiprazole have been reported.^4-8