Brainstorms January 15, 1998

Brain Fumes: Yes, We Have NO Brain Gas

Stephen M. Stahl

J Clin Psychiatry 1998;59(1):6-7

Article Abstract

Nitrous oxide (N2O) is "laughing gas," one of the earliest known inhalation anesthetics. Nitric oxide (NO) is a far different gas, although the two are often confused. It is NO that is made by the brain and used as a neurotransmitter, not N2O. Incredible as it may appear, NO, a poisonous unstable gas, which is part of car fumes and helps deplete the ozone layer, is also a chemical messenger both in the brain and in blood vessels.