Case Report May 15, 2013

Single-Photon Emission Computed Tomography Findings in a Patient With Fahr Disease Associated With a Schizophrenia-Like Psychosis

Laurent Boyer, MD, PhD; Eric Guedj, MD, PhD; Raphaëlle Richieri, MD; Florence Vaillant, MS; Christophe Lancon, MD, PhD

J Clin Psychiatry 2013;74(5):e431-e432

Article Abstract

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Fahr disease is a rare sporadic or familial idiopathic basal ganglia calcification associated with neurologic disorders, such as movement disturbances and dementia. More rarely, schizophrenia-like psychosis characterized by paranoia, hallucinations, and delusions has also been reported to be associated with Fahr disease. This second type of case associated with Fahr disease may help clinicians better understand the mechanisms underlying neuropsychiatric symptoms that are critical for future rational drug discovery in schizophrenia.

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