A Case of Ziprasidone-Induced Mania and the Role of 5-HT2A in Mood Changes Induced by Atypical Antipsychotics

Letter to the Editor

Sir: There have been documented cases of mania/ hypomania induced by various atypical antipsychotics. However, on the basis of MEDLINE and PubMed searches using the keywords mania, hypomania, atypical antipsychotics, risperidone, olanzapine, clozapine, ziprasidone, and quetiapine, mania triggered by ziprasidone has not been reported in the literature, which may be due to the relatively novel status of ziprasidone as an atypical antipsychotic. Here, we report a case of ziprasidone-induced mania.