Clozapine-Induced Pericarditis, Pericardial Tamponade, Polyserositis, and Rash

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Sir: Clozapine is an antipsychotic medication introduced tothe United States in 1989. It is a tricyclic dibenzodiazepine derivativechemically related to the traditional antipsychoticmedication loxapine.¹ Side effects pose a significant problemduring clozapine therapy.’ ‹