Article December 14, 2007

Cognitive Deficits in Patients With Schizophrenia: Effects and Treatment

Richard S. E. Keefe, PhD

J Clin Psychiatry 2007;68(suppl 14):8-13

Article Abstract

The average patient with schizophrenia performs on cognitive tests at the lowest 5% to 10% of the general population. Cognitive impairments impact patients on virtually every aspect of functioning, interfere with patients’ ability to engage in real-world tasks, and affect long-term outcome. Therefore, cognitive deficits should be included in the diagnostic criteria for schizophrenia. Clinicians need to focus treatment options on helping patients to regain premorbid levels of cognitive functioning.