Cognitive Facilitation and Behavioral Disinhibition With Benzodiazepine: A Case Report

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Sir: Although paradoxical effects of γ-aminobutyric acid (GABA)-ergic medications (excitation instead of sedation) are well-known, they have received no satisfactory explanation. We report the case of a 54-year-old woman with schizophrenia, in which we were able to observe this clinical pattern and its neural correlates.

Case report. The patient was in her forties, working as an assistant professor at a university, when she developed mostly negative symptoms.’ ‹