Letter to the Editor February 15, 2006

Dr. Finn and Colleagues Reply

Christine T. Finn, MD; Deborah Blacker, MD, ScD; Pamela Sklar, MD, PhD; Jordan W. Smoller, MD, ScD

J Clin Psychiatry 2006;67(2):324-325

Article Abstract

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Sir: We thank Drs. Feinberg and Moldawsky for their comments and agree with their cautions regarding the communication of genetic risks to patients and their families. As Dr. Feinberg notes, empirical recurrence risk estimates available from family studies of psychiatric illnesses lack precision. Of course, this is a problem that applies to many complex disorders, but is a particular issue in psychiatry, where diagnostic criteria and their implementation can have a significant impact on rates.’ ‹