Effects of the Traditional Chinese Herbal Medicine Yi-Gan San for Cholinesterase Inhibitor-Resistant Visual Hallucinations and Neuropsychiatric Symptoms in Patients With Dementia With Lewy Bodies

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Sir: Dementia with Lewy bodies (DLB) is characterizedclinically by progressive and fluctuating cognitive decline, visualhallucinations, and parkinsonism.¹ Some studies have reportedthat cholinesterase inhibitors are at least partiallybeneficial for treating patients with DLB.^2-4 However, Shea etal.⁵ reported that cholinesterase inhibitors occasionally causeddeterioration of parkinsonian symptoms in patients with DLB.’ ‹