The Emergency Treatment of Depression Complicated by Psychosis or Agitation

With the availability of newer, safer antidepressants in the past decade, initiation of definitivetreatment for depression in the emergency setting has become an accepted practice. However, the useof newer antidepressants and atypical antipsychotics in depression complicated by psychosis or agitationhas not yet been well studied. This article will review relevant data and make recommendationsfor the emergency management of psychotic and agitated depressive syndromes.