Grumpy Old Men (and Women): Mere Hassle or Meaningful Clinical Evidence?

The discovery of a prodromal or transitional state between normal aging and dementia has generated T a great deal of interest. Mild cognitive impairment (MCI) describes cognitive impairment in older individuals that is not of sufficient severity for a diagnosis of dementia. Individuals with MCI have impairments in memory or other cognitive functions that are usually noticeable to those around them.