Supplement Article October 1, 2003

Guidelines

John M. Kane, MD; Stefan Leucht, MD; Daniel Carpenter, PhD; John P. Docherty, MD

J Clin Psychiatry 2003;64(suppl 12):21-51

Article Abstract

Because this piece has no abstract, we have provided for your benefit the first 3 sentences of the full text.

For a first-episode patient with predominantly positive symptoms, the experts consider oral risperidone the treatment ofchoice. Other recommended medications for this clinical situation are aripiprazole, olanzapine, ziprasidone, and quetiapine(although the first two were rated first line and the second two high second line, these options clustered togetherand all were rated first line by approximately two-thirds of the experts).

For a first-episode patient with predominantly negative symptoms, the experts recommend one of the newer oral atypicalantipsychotics.