The Journal of
Clinical Psychiatry

Psychopharmacology

Brainstorms October 1, 2001

"Hit-and-Run" Actions at Dopamine Receptors, Part 2: Illustrating Fast Dissociation From Dopamine Receptors That Typifies Atypical Antipsychotics

Stephen M. Stahl

J Clin Psychiatry 2001;62(10):747-748

Article Abstract

Brainstorms:

In last month’s BRAINSTORMS, we discussed a new hypothesis on the mechanism of action of atypical antipsychotics, namely the "hit-and-run" hypothesis.Here we illustrate this concept.

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"Hit-and-Run" Actions at Dopamine Receptors, Part 2: Illustrating Fast Dissociation From Dopamine Receptors That Typifies Atypical Antipsychotics

Read the Current Issue

Focus on Women’s Mental Health: Twenty Years and Counting

Esmethadone in Patients With Major Depressive Disorder and Inadequate Response to Standard Antidepressants

Can Our Collective Experiences As Clinicians Improve Mental Health Care?

Prescription Opioid Use Disorder in US Adults Reporting Prescription Opioid Use

Symptomatic Disorders Comorbid with Borderline Personality Disorder Over Time

Aripiprazole Lauroxil Initiation Regimens

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FOLLOW US:

"Hit-and-Run" Actions at Dopamine Receptors, Part 2: Illustrating Fast Dissociation From Dopamine Receptors That Typifies Atypical Antipsychotics

Read the Current Issue

Focus on Women’s Mental Health: Twenty Years and Counting

Esmethadone in Patients With Major Depressive Disorder and Inadequate Response to Standard Antidepressants

Can Our Collective Experiences As Clinicians Improve Mental Health Care?

Prescription Opioid Use Disorder in US Adults Reporting Prescription Opioid Use

Symptomatic Disorders Comorbid with Borderline Personality Disorder Over Time

Aripiprazole Lauroxil Initiation Regimens

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