Reassessing a patient’s diagnosis if he or she does not respond adequately to initial antidepressant pharmacotherapy is imperative. In this CME activity, evaluate the case of Melissa, a 32-year-old architect with a potential case of treatment-resistant depression, and decide on appropriate treatment strategies.
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The Journal of Clinical Psychiatry
The Primary Care Companion for CNS Disorders
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Vol 87 • 2026 • Number 1
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ASCP Corner
Rethinking Amisulpride: Could N-Methylation Result in a New and Even Better Antipsychotic?
Original Research
How Many Criteria Should be Required to Define the DSM-5 Mixed Features Specifier in Depressed Patients?
Meta-Analysis
Effectiveness of Peer-Administered Interventions for Perinatal Depression or Anxiety
Original Research
Innovation in Psychiatric Drug Development: A Quantitative Analysis of FDA-Approved Psychiatric Drugs, 2012–2024
Brief Report
Exercise Reduces Dysphoria in Clinical High-Risk for Psychosis: A Randomized Controlled Trial
Clinical and Practical Psychopharmacology