What Do We Know About Insulin Resistance and Glucose Metabolism in Patients With Schizophrenia Treated With Antipsychotics?

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Sir: In their recent article on glucose metabolism in schizophrenic patients during treatment with olanzapine or quetiapine, Henderson et al.¹ have raised some important issues.

We wish to begin by complimenting the authors on their efforts to clarify a complex issue that attracts much attention in the literature. Their article is important for hypothesis generation in the area of understanding insulin resistance issues among patients treated with antipsychotics.’ ‹