Article January 9, 2001

Introduction: Weight Gain and Glucose Regulation During Antipsychotic Drug Treatment

Norman Sussman, MD

J Clin Psychiatry 2001;62(suppl 23):3-4

Article Abstract

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Excessive increases in body weight as a treatment-emergent effect of atypical antipsychoticdrugs has become the focal point of clinical and research interest. Weight gain has long been recognized as a potential side effect of treatment with conventional antipsychoticagents. The lack of demonstrable differences among these older compounds with respectto the incidence and degree of increased body weight made the issue largely irrelevantfrom a drug selection perspective. After all, not much could be done to avoid the problem.The current situation is different.’ ‹