Introduction. Ziprasidone in Schizophrenia: From Acute Treatment to Long-Term Management

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Schizophrenia is a highly complex, chronic, often lifelong, mental illness that severely compromises social, intellectual, and occupational functioning. About 1% ofthe population will develop schizophrenia, and annuallymore than 2 million Americans suffer from the disorder.¹People with schizophrenia on average live 15 fewer yearsthan individuals in the general population, dying prematurely of natural (e.g., cardiovascular and respiratory diseases) as well as unnatural causes (primarily suicide).²‘ ‹