Letter to the Editor March 18, 2008

Late-Onset Hypersensitivity Reaction With Leukopenia and Thrombocytopenia Induced by Oxcarbazepine Treatment in a Patient With Schizoaffective Disorder

Yi-Wei Yeh, MD; Tzu-Yun Wang, MD; Chang-Chih Huang, MD; Yi-Chyan Chen, MD, PhD

J Clin Psychiatry 2008;69(4):676-678

Article Abstract

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Sir: Oxcarbazepine is an anticonvulsant with similar chemicalstructure to carbamazepine.1 Oxcarbazepine is not only effectivein epileptic therapy, but also useful in the treatmentof refractory bipolar and schizoaffective disorders.1-5 Comparedto carbamazepine, rare hematologic suppression side-effect hadbeen reported with oxcarbazepine treatment.6-8‘ ‹