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The Journal of
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The Journal of Clinical Psychiatry

ASCP Corner August 13, 2026

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2026
Clinical Pearls

Switching stable schizophrenia from an oral atypical to xanomeline–trospium

SWITCH trial · Walling et al. · SIRS/ASCP 2026 · NCT06924255 · 2-week vs 4-week taper

Trial At A Glance

XX
Randomized
XX%
Completed switch
XX wk
Follow-up
2-week taper

XX%
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4-week taper

XX%
Placeholder endpoint — 4-wk arm (plum)
Expert consensus

Panel Guidance

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  • Placeholder consensus point three.
✓

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Psychiatrist.com Clinical Pearls · source: Walling et al., SIRS/ASCP 2026 · for scoping test only — stats are placeholders.


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The Journal of Clinical Psychiatry June 2026 cover with featured article titles

Vol 87 • 2026 • Number 2

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