Brainstorms April 15, 2003

At Long Last, Long-Lasting Psychiatric Medications: An Overview of Controlled-Release Technologies

Stephen M. Stahl, MD, PhD

J Clin Psychiatry 2003;64(4):355-356

Article Abstract
At Long Last, Long-Lasting Psychiatric Medications: An Overview of Controlled-Release Technologies.

Technologies that can change the delivery characteristics of drugs have been around for decades, but there has been a recent acceleration in the pace of their adaptation to psychiatric medications. Most notable is the increasing availability of numerous agents in oral sustained-release formulations that increase a drug’s duration of action. By allowing the frequency of dosing to be reduced from 2 or 3 times a day to once a day, compliance can be greatly enhanced.