Letter to the Editor May 14, 2009

Lupus Anticoagulant and Anticardiolipin Antibodies in Serum of Patients Treated With Risperidone

Miguel Schwartz; Maria Kormilachev; Mina Kushnir; Boaz Weller; Marina Rochas; Elias Toubi

J Clin Psychiatry 2009;70(5):769-771

Article Abstract

Letter to the Editor

Sir: In recent years, several studies reported an increasedrate of cerebrovascular events in patients treated with risperidone.In April 2005, the U.S. Food and Drug Administration issueda health advisory warning concerning an increased risk ofdeath among patients with dementia who were treated withatypical antipsychotic agents.

Risperidone is a second-generation antipsychotic agent thatreportedly increases the blood level of glucose and alterschanges in lipid profiles.